Distinct recurrence patterns according to disease manifestation in pilonidal sinus disease treated with cleft lift surgery at 5 years' follow-up in a large prospective Danish cohort.

IF 2.9 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Colorectal Disease Pub Date : 2024-11-17 DOI:10.1111/codi.17238
Natashja Pedersen, Ida Kaad Faurschou, Julie Lykke Ankersen, Marlene Julia Sørensen, Mikkel Lønborg Friis, Allan Gorm Pedersen, Dietrich Doll, Susanne Haas
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Abstract

Aim: Pilonidal sinus disease (PSD) is a common condition particularly affecting the young population. The disease is incompletely understood, and optimal treatment is still debated. However, off-midline closure techniques have become the standard of care in more advanced cases. The literature is, however, lacking disease stratification in evaluation of surgical results. The aim of this study was to evaluate the surgical outcomes in a prospective cohort following Bascom's cleft lift (BCL) in primary extensive disease, nonhealing wounds after previous surgery and recurrence on a large Danish cohort from a high-volume centre.

Method: The study is based on a prospective database established at Randers Regional Hospital in 2016. All patients undergoing BCL surgery from June 2016 until June 2020 were included in this study.

Results: Three hundred and ninety two patients (326 men/66 women) underwent BCL surgery over a 4-year period. Of these, 127 (32.4%) presented with primary extensive PSD, 136 (34.7%) with nonhealing wounds and 129 (33.9%) with recurrent PSD. Overall, 87% healed uneventfully within the first 3 months, and 17% had recurrence at a median follow-up of 60 months (45-73 months). However, the risk of recurrence was higher among patients with nonhealing wounds (20%) and recurrence (17%) compared with primary extensive manifestation (13%).

Conclusion: Treatment of advanced PSD remains challenging with a high rate of wound complications and recurrences, stressing the need for dedicated care. Patients with either failed surgery or recurrence need particular attention.

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在一个大型前瞻性丹麦队列中,对采用裂隙提升手术治疗的朝天鼻窦疾病进行 5 年随访,发现不同疾病表现的复发模式各不相同。
目的:蝶窦疾病(PSD)是一种常见病,尤其影响年轻人群。人们对该病的认识尚不全面,最佳治疗方法也仍存在争议。不过,中线外闭合技术已成为治疗晚期病例的标准方法。然而,文献在评估手术效果时缺乏疾病分层。本研究的目的是在一个前瞻性队列中评估原发性广泛性疾病、既往手术后伤口不愈合和复发的巴氏裂提升术(BCL)的手术效果:该研究基于兰德斯地区医院2016年建立的前瞻性数据库。从 2016 年 6 月至 2020 年 6 月接受 BCL 手术的所有患者均纳入本研究:392名患者(326名男性/66名女性)在4年时间内接受了BCL手术。其中,127 人(32.4%)患有原发性大面积 PSD,136 人(34.7%)患有伤口不愈合,129 人(33.9%)患有复发性 PSD。总体而言,87%的患者在最初 3 个月内顺利痊愈,17%的患者在中位随访 60 个月(45-73 个月)后复发。然而,与原发性广泛表现(13%)相比,伤口不愈合(20%)和复发(17%)患者的复发风险更高:结论:晚期 PSD 的治疗仍具有挑战性,伤口并发症和复发率较高,因此需要专门的护理。手术失败或复发的患者需要特别关注。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Colorectal Disease
Colorectal Disease 医学-胃肠肝病学
CiteScore
6.10
自引率
11.80%
发文量
406
审稿时长
1.5 months
期刊介绍: Diseases of the colon and rectum are common and offer a number of exciting challenges. Clinical, diagnostic and basic science research is expanding rapidly. There is increasing demand from purchasers of health care and patients for clinicians to keep abreast of the latest research and developments, and to translate these into routine practice. Technological advances in diagnosis, surgical technique, new pharmaceuticals, molecular genetics and other basic sciences have transformed many aspects of how these diseases are managed. Such progress will accelerate. Colorectal Disease offers a real benefit to subscribers and authors. It is first and foremost a vehicle for publishing original research relating to the demanding, rapidly expanding field of colorectal diseases. Essential for surgeons, pathologists, oncologists, gastroenterologists and health professionals caring for patients with a disease of the lower GI tract, Colorectal Disease furthers education and inter-professional development by including regular review articles and discussions of current controversies. Note that the journal does not usually accept paediatric surgical papers.
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