Natural Compounds and Cancer: Current Evidences.

Aikaterini D Lianou, Georgios D Lianos, Dimitrios Schizas, Nikolaos Machairas, Michail Mitsis, George A Alexiou
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Abstract

Natural compounds are constantly gaining ground in the treatment of various chronic diseases and in cancer research. Recent efforts have been focusing on them due to their special features consisting of low toxicity and high bioavailability. These compounds have already demonstrated important antitumor activity against several cancers in vitro through several mechanisms, including cell viability reduction, suppression of cell proliferation, cell death induction and cell cycle arrest. Herewith, we reviewed natural compounds that can be potentially used for head and neck cancer, glioblastoma and gastrointestinal cancers.

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天然化合物与癌症:当前证据。
天然化合物在治疗各种慢性疾病和癌症研究中的应用日益广泛。由于天然化合物具有低毒性和高生物利用度的特点,最近的研究重点一直放在它们身上。这些化合物已经通过多种机制,包括降低细胞活力、抑制细胞增殖、诱导细胞死亡和细胞周期停滞,在体外对多种癌症表现出了重要的抗肿瘤活性。在此,我们综述了可用于治疗头颈部癌症、胶质母细胞瘤和胃肠道癌症的天然化合物。
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