Study on the Relaxation Time Characteristics of Brain Tissue Based on Multi-Parametric Quantitative Magnetic Resonance Imaging

Jianhui Ren, Yuqin Zhang
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Abstract

Traditional magnetic resonance imaging (MRI) is qualitative imaging, and doctors need to rely on experience to diagnose diseases, which cannot meet the current needs of precision medicine. As a new quantitative magnetic resonance imaging technology, magnetic resonance fingerprint imaging can obtain a variety of human tissue parameters at the same time through a data acquisition, which greatly improves the imaging speed and improves the impact of noise on image quality. Several pattern matching algorithms are compared, including direct matching method, Bloch response iterative projection method, covering tree and approximate nearest neighbor search method, and improved methods. Absolute error image, mean absolute error (MAE), normalized root means square error (RMSE) and running time are counted in the experimental results. The results show that the improved method is better than the traditional method, which can greatly improve the quality of MR fingerprint multi-parameter images (T1, T2, B0, PD), and make the running time within an acceptable range. In addition, the improved algorithm is insensitive to random additive noise.
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基于多参数定量磁共振成像的脑组织松弛时间特征研究
传统的磁共振成像(MRI)属于定性成像,医生需要依靠经验诊断疾病,无法满足当前精准医疗的需求。磁共振指纹成像作为一种新型的定量磁共振成像技术,通过一次数据采集可同时获得多种人体组织参数,大大提高了成像速度,改善了噪声对图像质量的影响。比较了几种模式匹配算法,包括直接匹配法、布洛赫响应迭代投影法、覆盖树和近似近邻搜索法以及改进方法。实验结果包括图像绝对误差、平均绝对误差(MAE)、归一化均方根误差(RMSE)和运行时间。结果表明,改进方法优于传统方法,能大大提高磁共振指纹多参数图像(T1、T2、B0、PD)的质量,并使运行时间在可接受的范围内。此外,改进算法对随机加性噪声不敏感。
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