Reinforced Borrowing Framework: Leveraging Auxiliary Data for Individualized Inference.

Abstract

Increasingly during the past decade, researchers have sought to leverage auxiliary data for enhancing individualized inference. Many existing methods, such as multisource exchangeability models (MEM), have been developed to borrow information from multiple supplemental sources to support parameter inference in a primary source. MEM and its alternatives decide how much information to borrow based on the exchangeability of the primary and supplemental sources, where exchangeability is defined as equality of the target parameter. Other information that may also help determine the exchangeability of sources is ignored. In this article, we propose a generalized reinforced borrowing framework (RBF) leveraging auxiliary data for enhancing individualized inference using a distance-embedded prior which uses data not only about the target parameter but also uses different types of auxiliary information sources to "reinforce" inference on the target parameter. RBF improves inference with minimal additional computational burden. We demonstrate the application of RBF to a study investigating the impact of the COVID-19 pandemic on individual activity and transportation behaviors, where RBF achieves 20%-40% lower MSE compared with existing methods.