Anorexia Nervosa in Comorbidity With Borderline Personality Disorder in Adolescence: A Specific Clinical Endophenotype?

IF 3.9 2区心理学 Q1 PSYCHIATRY European Eating Disorders Review Pub Date : 2024-11-18 DOI:10.1002/erv.3155

Anna Riva, Eleonora Brasola, Sofia Elena Sforza, Mirella Marfone, Francesco Biso, Renata Nacinovich

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Abstract

Objective

Anorexia nervosa and borderline personality disorder are often associated and share some core elements, including emotional dysregulation and affective instability. Nevertheless, the association of these two conditions in adolescence is still little studied.

Method

The present study aims at investigating, through a multidimensional assessment, the psychopathological characteristics of adolescents affected by anorexia nervosa in comorbidity with borderline personality disorder on a sample of 127 female adolescents, through the comparison with adolescents with borderline personality disorders and adolescents with anorexia nervosa. All participants completed a validated psychometric battery assessing alexithymia (Toronto Alexithymia Scale-20), depression (Children's Depression Inventory), psychological symptoms (Symptom Checklist-90–Revised) and psychological symptoms relevant in eating disorders (Eating Disorders Inventory-3).

Results

Adolescents with anorexia nervosa in comorbidity with borderline personality disorder show intermediate features between the two disorders individually in the general psychopathological profile, but a peculiar psychological profile regarding the eating symptomatology, with worse features compared to adolescents with the sole anorexia nervosa.

Conclusions

Results suggest a peculiar clinical and psychopatological endophenotype in adolescents with anorexia nervosa in comorbidity with borderline personality disorders, indicating the need to define specific and tailored treatment for this population.

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青春期神经性厌食症与边缘型人格障碍合并症：一种特殊的临床内表型？

目的：神经性厌食症和边缘型人格障碍常常相互关联，并具有一些共同的核心要素，包括情绪失调和情感不稳定。然而，关于这两种疾病在青少年时期的关联性研究仍然很少：本研究以127名女性青少年为样本，通过与患有边缘型人格障碍的青少年和患有神经性厌食症的青少年进行比较，旨在通过多维度评估，调查患有神经性厌食症的青少年与患有边缘型人格障碍的青少年的心理病理特征。所有参与者都完成了一项有效的心理测试，该测试评估了厌食症（多伦多厌食症量表-20）、抑郁症（儿童抑郁量表）、心理症状（症状检查表-90-修订版）以及与进食障碍相关的心理症状（进食障碍量表-3）：结果：合并有神经性厌食症和边缘型人格障碍的青少年在一般精神病理特征方面表现出介于这两种疾病之间的特征，但在进食症状方面却表现出特殊的心理特征，与单纯患有神经性厌食症的青少年相比，其特征更为严重：结论：研究结果表明，神经性厌食症合并边缘型人格障碍的青少年有一种特殊的临床和心理病理内表型，表明有必要为这一人群确定专门的、有针对性的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Eating Disorders Review PSYCHOLOGY, CLINICAL-

CiteScore

8.90

自引率

7.50%

发文量

期刊介绍： European Eating Disorders Review publishes authoritative and accessible articles, from all over the world, which review or report original research that has implications for the treatment and care of people with eating disorders, and articles which report innovations and experience in the clinical management of eating disorders. The journal focuses on implications for best practice in diagnosis and treatment. The journal also provides a forum for discussion of the causes and prevention of eating disorders, and related health policy. The aims of the journal are to offer a channel of communication between researchers, practitioners, administrators and policymakers who need to report and understand developments in the field of eating disorders.