Takahiro Sawano, Manami Kobayashi, Momoko Ishikawa, Eri Ishikawa, Ryo Takeuchi
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Abstract
We report an allenylic substitution of racemic tertiary allenylic alcohols with indoles by a cooperative catalyst consisting of iridium/(P, olefin)-ligand catalyst and Lewis acid to give allenylated indoles bearing a quaternary carbon center with good enantioselectivities. 7-Azaindoles also reacted with allenylic alcohols to form the corresponding allenylated products with high enantioselectivities.
期刊介绍：
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
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