Transcatheter arterial embolization therapy in patients with polycystic kidney disease and liver disease: review from case series.

IF 2.2 4区 医学 Q2 UROLOGY & NEPHROLOGY Clinical and Experimental Nephrology Pub Date : 2024-11-20 DOI:10.1007/s10157-024-02597-1
Yoshifumi Ubara, Tatsuya Suwabe, Naoki Sawa
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Abstract

We have achieved good results of renal transarterial embolization (TAE) therapy as an alternative to surgical nephrectomy to decrease renal size in autosomal polycystic kidney disease (ADPKD) patients with enlarged kidneys, but only in patients on dialysis. Renal transplantation is another treatment option, and patients who receive a donor kidney have achieved a reduction in kidney size after surgery. TAE has also been used in polycystic liver disease (PCLD), an extrarenal lesion of ADPKD. Although TAE is effective in some PCLD patients, others develop hepatomegaly, which leads to liver cyst infection and liver failure. Recently, liver transplantation has started to be performed in such patients. Initially, living donor liver transplants were performed from family members, but in 2010, deceased donor liver transplantation became available. This article gives an overview of the history of TAE for ADPKD and PCLD on the basis of our experience.

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多囊肾和肝病患者的经导管动脉栓塞疗法:系列病例回顾。
对于肾脏肿大的常染色体多囊肾病患者,我们采用肾脏经动脉栓塞疗法(TAE)替代手术肾切除术来缩小肾脏体积,取得了良好的效果,但仅限于透析患者。肾移植是另一种治疗方法,接受捐赠肾脏的患者在手术后肾脏体积会缩小。TAE还被用于多囊肝病(PCLD),这是ADPKD的肾外病变。虽然TAE对一些PCLD患者有效,但其他患者会出现肝肿大,导致肝囊肿感染和肝功能衰竭。最近,这类患者开始接受肝移植。最初,活体肝移植是由家庭成员进行的,但在2010年,开始出现了死亡供体肝移植。本文根据我们的经验概述了ADPKD和PCLD TAE的历史。
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来源期刊
Clinical and Experimental Nephrology
Clinical and Experimental Nephrology UROLOGY & NEPHROLOGY-
CiteScore
4.10
自引率
4.30%
发文量
135
审稿时长
4-8 weeks
期刊介绍: Clinical and Experimental Nephrology is a peer-reviewed monthly journal, officially published by the Japanese Society of Nephrology (JSN) to provide an international forum for the discussion of research and issues relating to the study of nephrology. Out of respect for the founders of the JSN, the title of this journal uses the term “nephrology,” a word created and brought into use with the establishment of the JSN (Japanese Journal of Nephrology, Vol. 2, No. 1, 1960). The journal publishes articles on all aspects of nephrology, including basic, experimental, and clinical research, so as to share the latest research findings and ideas not only with members of the JSN, but with all researchers who wish to contribute to a better understanding of recent advances in nephrology. The journal is unique in that it introduces to an international readership original reports from Japan and also the clinical standards discussed and agreed by JSN.
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