Hypersensitivity Pneumonitis: The Diagnosis Lies in History.

Jyoti Chauhan, Tanvi Batra, Atul Kakar, Rahul Kumar, Naveen Goud Bollapally, Anjana Jangid
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Abstract

Hypersensitivity pneumonitis (HP)/extrinsic allergic alveolitis (EAA) is defined as a response of lungs to inhaled organic and inorganic substances. This disease is relatively rare, comprising 2% of cases in the category of interstitial lung diseases. Here, we discuss a case of 61-year-old female, who presented with sudden onset breathlessness, with bilateral coarse crackles on physical examination, initially thought to be due to heart failure or atypical pneumonia, but later diagnosed as HP. She was managed initially with antibiotics but due to poor response, steroids were introduced which led to significant improvement. This report emphasizes the importance of exposure history of substances that are toxic, lack of specificity of clinical manifestations, importance of invasive methods for diagnosis, and poor response to therapy in case of delayed diagnosis.

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超敏性肺炎:诊断在于病史
超敏性肺炎(HP)/外源性过敏性肺泡炎(EAA)被定义为肺部对吸入的有机和无机物质的反应。这种疾病相对罕见,只占间质性肺病病例的 2%。在此,我们讨论一例 61 岁的女性患者,她突然出现呼吸困难,体格检查时出现双侧粗大的噼啪声,起初以为是心力衰竭或非典型肺炎所致,但后来被诊断为 HP。起初她接受了抗生素治疗,但由于反应不佳,医生开始使用类固醇,结果病情明显好转。本报告强调了接触有毒物质史的重要性、临床表现缺乏特异性、侵入性诊断方法的重要性以及延误诊断时治疗反应差等问题。
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