Status Epilepticus in Children: Risk Factors and Clinical Evaluation.

Q3 Medicine Tunisie Medicale Pub Date : 2024-11-05 DOI:10.62438/tunismed.v102i11.4493
Asma Marzouk, Ilyes Ben Yahia, Meriem Lajili, Nour Jlaila, Rahma Thebti, Asma Bouaziz
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Abstract

Introduction and aim: Status epilepticus (SE) in children is a critical condition that can be life-threatening. The objective of this study was to identify factors associated with the occurrence of SE after a first convulsive seizure in children.

Methods: A retrospective study was conducted at the pediatric department of BEN AROUS regional hospital between January 2015 and December 2019.

Results: A total of 300 patients admitted for a first epileptic seizure were included in this analysis. The mean age of the patients was 33 months. Seizures were generalized in 92.7%, with tonic-clonic seizures being the most common (54.8%). SE was diagnosed as inaugural in 29% of cases. Abnormalities in EEG were observed in 36.5% of cases, while MRI revealed abnormal results in 32.8% of patients. Factors associated with a risk of SE recurrence were age younger than 1 year (p = 0.003), neuromotor retardation (p = 0.001), EEG abnormalities (p < 0.001), MRI abnormalities (p = 0.001), and abrupte discontinuation of antiepileptic treatment (p < 0.001). Simple febrile seizure was identified as a protective factor (p = 0.038).

Conclusion: The study identified that age under 1 year, neuromotor delay, and abnormalities in EEG and MRI are significant risk factors for the recurrence of status epilepticus after a first epileptic seizure in children. These findings suggest targeted preventive strategies to improve the management and prognosis of these patients.

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儿童癫痫状态:风险因素与临床评估。
导言和目的:儿童癫痫状态(SE)是一种危急情况,可能危及生命。本研究旨在确定与儿童首次惊厥发作后发生癫痫状态相关的因素:2015年1月至2019年12月期间,本阿鲁斯地区医院儿科开展了一项回顾性研究:本次分析共纳入了 300 名因首次癫痫发作而入院的患者。患者的平均年龄为 33 个月。92.7%的患者为全身性发作,其中强直阵挛发作最为常见(54.8%)。29%的病例被诊断为癫痫发作。36.5%的病例出现脑电图异常,32.8%的患者出现磁共振成像异常。与 SE 复发风险相关的因素有:年龄小于 1 岁(p = 0.003)、神经运动发育迟缓(p = 0.001)、脑电图异常(p < 0.001)、磁共振成像异常(p = 0.001)和中断抗癫痫治疗(p < 0.001)。单纯发热性癫痫发作被认为是一个保护因素(p = 0.038):研究发现,年龄不足 1 岁、神经运动发育迟缓、脑电图和磁共振成像异常是儿童首次癫痫发作后癫痫状态复发的重要风险因素。这些发现建议采取有针对性的预防策略,以改善这些患者的管理和预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Tunisie Medicale
Tunisie Medicale Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
72
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