Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model.

IF 7 2区 医学 Q1 BIOLOGY Computers in biology and medicine Pub Date : 2024-11-19 DOI:10.1016/j.compbiomed.2024.109432
Shahriar Mohammadi, Mohammad Ahmadi Livani
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Abstract

Breast mass segmentation plays a crucial role in early breast cancer detection and diagnosis, and while Convolutional Neural Networks (CNN) have been widely used for this task, their reliance on local receptive fields limits ability to capture long-range dependencies. Vision Transformers (ViTs), on the other hand, excel in this area by leveraging multi-head self-attention mechanisms to generate attention maps that dynamically gather global spatial information, significantly outperforming CNN-based architectures in various tasks. However, traditional transformer-based models come with challenges, including high computational complexity due to the self-attention mechanism and inefficiency in the static MLP fusion process. To overcome these issues, the Hybrid Transformer U-Net (HTU-net) model is proposed for breast mass segmentation in mammography. Channel and spatial enhanced self-attention mechanisms are integrated with convolutions layers in HTU-Net, creating a hybrid architecture that combines the strengths of both CNNs and ViTs. The introduction of a multiscale attention mechanism further improves the model's ability to fuse information from different resolutions, enhancing the decoder's capacity to reconstruct fine details in the segmented output. By using both local texture-based features and global contextual information, HTU-Net excels in capturing essential features, thus improving segmentation performance. The experimental results across multiple datasets, including CBIS-DDSM and INbreast, demonstrate that HTU-Net outperforms several state-of-the-art methods, achieving superior accuracy, dice similarity coefficient, and intersection over union. This work highlights the potential of hybrid architectures in advancing computer-aided diagnosis systems, particularly in improving segmentation quality and reliability for breast cancer detection.

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使用混合变压器 UNet 模型增强乳房 X 光照片中的乳房肿块分割。
乳房肿块分割在早期乳腺癌检测和诊断中起着至关重要的作用,虽然卷积神经网络(CNN)已被广泛应用于这项任务,但其对局部感受野的依赖限制了捕捉长距离依赖关系的能力。另一方面,视觉变换器(ViTs)在这一领域表现出色,它利用多头自我注意机制生成可动态收集全局空间信息的注意图,在各种任务中明显优于基于 CNN 的架构。然而,传统的基于变压器的模型也面临挑战,包括自注意机制导致的高计算复杂性和静态 MLP 融合过程的低效率。为了克服这些问题,我们提出了混合变换器 U-Net 模型(HTU-net),用于乳腺 X 射线摄影中的乳房肿块分割。HTU-Net 中的卷积层集成了通道和空间增强自注意机制,形成了一种混合架构,结合了 CNN 和 ViT 的优势。多尺度注意机制的引入进一步提高了模型融合不同分辨率信息的能力,增强了解码器在分割输出中重建精细细节的能力。通过同时使用基于纹理的局部特征和全局上下文信息,HTU-Net 在捕捉基本特征方面表现出色,从而提高了分割性能。包括 CBIS-DDSM 和 INbreast 在内的多个数据集的实验结果表明,HTU-Net 的表现优于几种最先进的方法,在准确性、骰子相似系数和相交优于联合方面都表现出色。这项工作凸显了混合架构在推进计算机辅助诊断系统方面的潜力,特别是在提高乳腺癌检测的分割质量和可靠性方面。
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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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