Chronic corticosteroid use does not increase short-term complications following carpometacarpal arthroplasty.

Kenny Ling, Nishank Mehta, Lekha Yaramada, Nishanth Muthusamy, Taylor VanHelmond, Edward D Wang
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Abstract

Purpose: Chronic steroid use has been found to be significantly associated with postoperative complications following total joint arthroplasty. The purpose of this study was to investigate the relationship between chronic steroid and immunosuppressant use and postoperative complications following carpometacarpal (CMC) arthroplasty.

Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried for all records of patients who underwent carpometacarpal (CMC) arthroplasty between 2015 and 2020. The initial pool of records was divided into two cohorts: chronic steroid and no chronic steroid use. Patient demographics and comorbidities were compared between cohorts using bivariate logistic regression.

Results: A total of 6624 records of CMC arthroplasty were identified in NSQIP from 2015 to 2020. Of the 6432 records remaining after exclusion criteria, 223 (3.5%) were chronic steroid use and 6209 (96.5%) were without chronic steroid use. The patient demographics and comorbidities significantly associated with chronic steroid use were ASA classification ≥ 3 (p < 0.001), insulin-dependent diabetes mellitus (p = 0.032), and COPD (p < 0.001). Compared to no chronic steroid use, chronic steroid use had higher rates of any complication (2.24% vs. 2.01%), superficial incisional SSI (1.35% vs. 0.63%), urinary tract infection (0.45% vs. 0.31%), sepsis (0.45% vs. 0.05%), and mortality (0.45% vs. 0.05%). However, these differences in complication rates were not statistically significant.

Conclusion: Chronic preoperative steroid use was not significantly associated with any increased postoperative complication within 30 days following CMC arthroplasty.

Level of evidence: Level III; Retrospective Cohort Comparison; Prognosis Study.

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长期使用皮质类固醇不会增加腕掌关节成形术后的短期并发症。
目的:研究发现,长期使用类固醇与全关节成形术后并发症密切相关。本研究旨在调查长期使用类固醇和免疫抑制剂与腕掌关节(CMC)成形术后并发症之间的关系:查询了美国外科医生学会国家外科质量改进计划数据库中2015年至2020年间接受腕掌(CMC)关节置换术患者的所有记录。最初的记录库分为两组:长期使用类固醇和未长期使用类固醇。采用双变量逻辑回归法比较不同组群的患者人口统计学特征和合并症:从 2015 年到 2020 年,NSQIP 共识别了 6624 份 CMC 关节置换术记录。在排除标准后剩余的 6432 条记录中,223 条(3.5%)长期使用类固醇,6209 条(96.5%)未长期使用类固醇。与长期使用类固醇显著相关的患者人口统计学特征和并发症是 ASA 分级≥ 3(P 结论:术前长期使用类固醇会导致术后并发症:术前长期使用类固醇与CMC关节置换术后30天内术后并发症的增加无明显关系:证据等级:III级;回顾性队列比较;预后研究。
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来源期刊
CiteScore
3.00
自引率
5.90%
发文量
265
审稿时长
3-8 weeks
期刊介绍: The European Journal of Orthopaedic Surgery and Traumatology (EJOST) aims to publish high quality Orthopedic scientific work. The objective of our journal is to disseminate meaningful, impactful, clinically relevant work from each and every region of the world, that has the potential to change and or inform clinical practice.
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