{"title":"Hybrid prediction model with improved score level fusion for heart disease diagnosis","authors":"Shaik Ghouhar Taj, K. Kalaivani","doi":"10.1016/j.compbiolchem.2024.108278","DOIUrl":null,"url":null,"abstract":"<div><div>Heart disease diagnosis is a challenging task, which provides an automated forecast of the patient's heart illness to make future treatment simpler. This has led to extensive interest in heart disease diagnostics in the medical sector. However, as there are various risks, the prediction must be more appropriate to avoid death. This work intends to develop the Hybrid Prediction Model with Improved Score Level Fusion (HPISLF) for Heart Disease Prediction. Preprocessing is the first process, where improved min-max normalization is done to preprocess the input data. Feature extraction plays a major role as it extracts additional information from the input data via extracting HOS, Improved Holoentropy-based features, and MI are extracted. Also, proposing a hybrid classification model for diagnosis, which trains the model with the extracted feature set. The final classification outcome is determined by the improved score level fusion that fuses the classification outcomes from both the classifiers, CNN and DeepMaxout. The performance of the proposed work is validated and compared over the conventional methods in terms of accuracy, precision, and other measures.</div></div>","PeriodicalId":10616,"journal":{"name":"Computational Biology and Chemistry","volume":"113 ","pages":"Article 108278"},"PeriodicalIF":2.6000,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computational Biology and Chemistry","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1476927124002664","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Heart disease diagnosis is a challenging task, which provides an automated forecast of the patient's heart illness to make future treatment simpler. This has led to extensive interest in heart disease diagnostics in the medical sector. However, as there are various risks, the prediction must be more appropriate to avoid death. This work intends to develop the Hybrid Prediction Model with Improved Score Level Fusion (HPISLF) for Heart Disease Prediction. Preprocessing is the first process, where improved min-max normalization is done to preprocess the input data. Feature extraction plays a major role as it extracts additional information from the input data via extracting HOS, Improved Holoentropy-based features, and MI are extracted. Also, proposing a hybrid classification model for diagnosis, which trains the model with the extracted feature set. The final classification outcome is determined by the improved score level fusion that fuses the classification outcomes from both the classifiers, CNN and DeepMaxout. The performance of the proposed work is validated and compared over the conventional methods in terms of accuracy, precision, and other measures.
期刊介绍:
Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.
Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.
Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.