A Case of Thoracic SMARCA4-Deficient Undifferentiated Tumor on 18F-FDG PET/CT.

Gege Zhao, Zhongke Huang
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Abstract

A 65-year-old man, who denied a smoking history, presented with chest distress and pain persisting for over a week. A contrast-enhanced chest CT scan revealed a large irregular mass in the right thoracic cavity with heterogeneous enhancement. The 18F-FDG PET/CT showed a large mass in the right thoracic cavity with heterogeneous markedly high FDG uptake. The patient subsequently underwent a bronchoscopic-guided mucosal biopsy at the opening of the right upper lobe. The histological and immunohistochemical findings were consistent with thoracic SMARCA4-deficient undifferentiated tumor.

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一例胸腔 SMARCA4 缺失型未分化肿瘤(18F-FDG PET/CT)。
一名否认有吸烟史的 65 岁男子因胸部不适和疼痛持续一周多而就诊。对比增强胸部 CT 扫描显示,右胸腔有一个巨大的不规则肿块,呈异质强化。18F-FDG PET/CT 显示右胸腔有一个巨大肿块,伴有异质性明显的高 FDG 摄取。患者随后在右上叶开口处接受了支气管镜引导下的粘膜活检。组织学和免疫组化结果与胸腔 SMARCA4 缺失性未分化肿瘤一致。
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