[Characteristics of melanoma in Mexicans seen at "La Raza" National Medical Center].

Blanca Carlos-Ortega, Ulises Ángeles-Garay, Marian Fernández-Martínez, Guillermo Gómez-Campos, Rodrigo Roldán-Marín
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Abstract

Background: Melanoma is the third most common type of skin cancer in Mexico and represents 75% of skin cancer deaths. Dermoscopy is a diagnostic tool that increases early detection of melanoma compared to naked eye examination.

Objective: The aim of this study was to describe the clinical, dermoscopic and histological characteristics of patients with a confirmed diagnosis of cutaneous melanoma treated at the "La Raza" National Medical Center.

Material and methods: A retrospective, descriptive and cross-sectional study was carried out from March 1998 to December 2013, with 187 histologically confirmed cases, considering: sex, age, skin phototype, history, topography of the lesion, dermoscopic pattern, metastasis at the time of diagnosis and histological subtype, Breslow index and Clark index, using the chi-square test as a non-parametric statistical method to analyze the data obtained.

Results: Most patients had skin phototype III and the most affected location was the lower limb. Clinically, acral lentiginous melanomas and nodular melanomas were the most observed. The most common dermoscopic finding was the multicomponent pattern. Clinically and histologically, the most frequent subtype associated with metastasis was nodular melanoma. Acral lentiginous melanoma was more common among patients without metastasis.

Conclusions: Unfortunately, melanoma is still diagnosed in advanced stages in Mexico; for its early recognition, training in the use of dermoscopy and greater awareness about melanoma in the Mexican population must be encouraged.

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[在 "La Raza "国家医疗中心就诊的墨西哥人中黑色素瘤的特征]。
背景:黑色素瘤是墨西哥第三大常见皮肤癌,占皮肤癌死亡人数的75%。与肉眼检查相比,皮肤镜是一种能提高黑色素瘤早期发现率的诊断工具:本研究旨在描述 "La Raza "国立医疗中心确诊的皮肤黑色素瘤患者的临床、皮肤镜检查和组织学特征:1998年3月至2013年12月期间,对187例经组织学确诊的病例进行了回顾性、描述性和横断面研究,考虑了性别、年龄、皮肤光型、病史、病变地形、皮肤镜形态、确诊时的转移情况和组织学亚型、布雷斯罗指数和克拉克指数,采用非参数统计方法卡方检验对所得数据进行分析:大多数患者的皮肤光型为 III 型,受影响最大的部位是下肢。临床上观察到的最多的是尖头皮损黑色素瘤和结节性黑色素瘤。最常见的皮肤镜检查结果是多组分模式。在临床和组织学上,与转移相关的最常见亚型是结节性黑色素瘤。在未发生转移的患者中,口腔扁平苔癣状黑色素瘤更为常见:遗憾的是,在墨西哥,黑色素瘤的诊断仍处于晚期阶段;为了及早识别黑色素瘤,必须鼓励对墨西哥人进行使用皮肤镜的培训,并提高他们对黑色素瘤的认识。
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