Pierre-Edouard Debureaux, Stéphanie Poulain, Stephanie Harel, Marie Passet, Marie Templé, Chloe Friedrich, Nathalie Forgeard, Dikelele Elessa, William Plas, Laureen Chat, Gregory Lazarian, Lise Willems, Bruno Royer, Alexis Talbot, Tristan Vaugeois, Floriane Theves, Alexandre Terré, Anne C Brignier, Marion Malphettes, Daphné Krzisch, Laurent Frenzel, Frédéric Davi, Clotilde Bravetti, Florence Nguyen-Khac, Jehan Dupuis, Wendy Cuccuini, Didier Bouscary, Olivier Hermine, Damien Roos-Weil, Olivier Kosmider, Emmanuelle Clappier, Marion Espéli, Karl Balabanian, Bertrand Arnulf
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引用次数: 0
Abstract
Inflammation in Waldenström Macroglobulinemia (iWM) predicts outcomes after immuno-chemotherapy and BTK inhibitors, but its origin is unknown. Here, we unravel increased clonal hematopoiesis in iWM patients (61% versus 23% in non-inflammatory WM), suggesting a contribution of environmental cells to iWM.
期刊介绍:
Blood, the official journal of the American Society of Hematology, published online and in print, provides an international forum for the publication of original articles describing basic laboratory, translational, and clinical investigations in hematology. Primary research articles will be published under the following scientific categories: Clinical Trials and Observations; Gene Therapy; Hematopoiesis and Stem Cells; Immunobiology and Immunotherapy scope; Myeloid Neoplasia; Lymphoid Neoplasia; Phagocytes, Granulocytes and Myelopoiesis; Platelets and Thrombopoiesis; Red Cells, Iron and Erythropoiesis; Thrombosis and Hemostasis; Transfusion Medicine; Transplantation; and Vascular Biology. Papers can be listed under more than one category as appropriate.