A paradigm shift in the detection of bloodborne pathogens: conventional approaches to recent detection techniques.

IF 3.8 3区 生物学 Q1 BIOLOGY EXCLI Journal Pub Date : 2024-10-17 eCollection Date: 2024-01-01 DOI:10.17179/excli2024-7392
Sonali Khanal, Manjusha Pillai, Deblina Biswas, Muhammad Torequl Islam, Rachna Verma, Kamil Kuca, Dinesh Kumar, Asim Najmi, Khalid Zoghebi, Asaad Khalid, Syam Mohan
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Abstract

Bloodborne pathogens (BBPs) pose formidable challenges in the realm of infectious diseases, representing significant risks to both human and animal health worldwide. The review paper provides a thorough examination of bloodborne pathogens, highlighting the serious worldwide threat they pose and the effects they have on animal and human health. It addresses the potential dangers of exposure that healthcare workers confront, which have affected 3 million people annually, and investigates the many pathways by which these viruses can spread. The limitations of traditional detection techniques like PCR and ELISA have been criticized, which has led to the investigation of new detection methods driven by advances in sensor technology. The objective is to increase the amount of knowledge that is available regarding bloodborne infections as well as effective strategies for their management and detection. This review provides a thorough overview of common bloodborne infections, including their patterns of transmission, and detection techniques.

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血液传播病原体检测模式的转变:从传统方法到最新检测技术。
血源性病原体(BBPs)在传染病领域构成了严峻的挑战,对全球人类和动物健康构成了重大风险。这篇综述论文对血源性病原体进行了深入研究,强调了它们在全球范围内造成的严重威胁及其对动物和人类健康的影响。它探讨了医护人员面临的潜在接触危险(每年有 300 万人受到影响),并研究了这些病毒传播的多种途径。聚合酶链式反应(PCR)和酶联免疫吸附试验(ELISA)等传统检测技术的局限性受到了批评,这促使人们开始研究由传感器技术进步推动的新检测方法。我们的目标是增加有关血源性感染的知识量,以及管理和检测血源性感染的有效策略。本综述全面概述了常见的血源性感染,包括其传播模式和检测技术。
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来源期刊
EXCLI Journal
EXCLI Journal BIOLOGY-
CiteScore
8.00
自引率
2.20%
发文量
65
审稿时长
6-12 weeks
期刊介绍: EXCLI Journal publishes original research reports, authoritative reviews and case reports of experimental and clinical sciences. The journal is particularly keen to keep a broad view of science and technology, and therefore welcomes papers which bridge disciplines and may not suit the narrow specialism of other journals. Although the general emphasis is on biological sciences, studies from the following fields are explicitly encouraged (alphabetical order): aging research, behavioral sciences, biochemistry, cell biology, chemistry including analytical chemistry, clinical and preclinical studies, drug development, environmental health, ergonomics, forensic medicine, genetics, hepatology and gastroenterology, immunology, neurosciences, occupational medicine, oncology and cancer research, pharmacology, proteomics, psychiatric research, psychology, systems biology, toxicology
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