[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report].

Óscar Andrés Ramírez-Terán, Eduardo Tomás-Alvarado
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Abstract

Background: Neonatal cardiac tumors are a rare pathology, with an approximate incidence of 0.017% in autopsies and 0.31% in obstetric echographies. The most common primary cardiac tumor is rhabdomyomas and its clinical manifestations are highly variable. Most patients do not require therapeutic management unless there is hemodynamic compromise, in which one option is surgical management, which implies high mortality. Rhabdomyomas are usually associated with tuberous sclerosis, a disease for which drugs such as everolimus or sirolimus have been used.

Clinical case: Newborn male patient with no significant history, in whom a cardiac arrhythmia was detected during the routine physical examination. After the evaluation by Pediatric Cardiology, it was determined that the patient had supraventricular extrasystoles, in addition to multiple intracardiac masses that, due to imaging characteristics, were compatible with rhabdomyomas, so it was determined that the cause of cardiac arrhythmia was the presence of multiple tumors. Due to the condition of the conduction system, everolimus and propranolol were used. After 7 days, control of the arrhythmias was achieved and resolution of the tumors was achieved after 8 weeks.

Conclusions: Rhabdomyomas are cardiac tumors associated with tuberous sclerosis, clinical complications can be managed effectively with everolimus as in the case presented.

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[心律失常是新生儿心脏肿瘤的首发症状:病例报告]。
背景:新生儿心脏肿瘤是一种罕见的病理现象,在尸检中的发病率约为 0.017%,在产科超声检查中的发病率约为 0.31%。最常见的原发性心脏肿瘤是横纹肌瘤,其临床表现千变万化。大多数患者不需要治疗,除非出现血流动力学损害,这时可以选择手术治疗,但这意味着高死亡率。横纹肌瘤通常与结节性硬化症有关,这种疾病已使用依维莫司或西罗莫司等药物治疗:新生儿男性患者,无明显病史,在常规体检中发现心律失常。经过小儿心脏科的评估,确定患者有室上性期外收缩,此外还有多个心内肿块,根据影像学特征,这些肿块与横纹肌瘤相符,因此确定心律失常的原因是存在多个肿瘤。鉴于传导系统的状况,使用了依维莫司和普萘洛尔。7 天后,心律失常得到控制,8 周后肿瘤消退:横纹肌瘤是与结节性硬化症相关的心脏肿瘤,临床并发症可以通过依维莫司得到有效控制,本病例就是如此。
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