Unsuspected Malignant Mimicry From Topical Vitamin E and Micro Spike Roller.

IF 2.3 3区 医学 Q1 OTORHINOLARYNGOLOGY Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-02-01 Epub Date: 2024-11-22 DOI:10.1002/hed.27996
Jacob Hauser, Traeden Wilson, Chelsea Huang, Paul Walker
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Abstract

Background: Topical vitamin E is commonly used for its antioxidant properties in a rapidly expanding anti-aging market. Cutaneous reaction to vitamin E is rare and can present a difficult diagnosis.

Methods: We report a unique case of a 46-year-old female who developed a severe cutaneous inflammatory chin lesion after topical use of vitamin E oil with a micro-spike roller. Clinical examination found a friable and fungating mass which prompted biopsy due to suspected malignancy. Pathology ruled out malignancy and revealed chronic inflammation with xanthogranulomatous-like features.

Results: The lesion was significantly improved with Kenalog injection treatment over 18 months. A scar excision procedure further enhanced the lesion cosmetically.

Conclusions: This case highlights the rarity and clinical diversity of vitamin E skin reactions, and their potential to mimic malignancies.

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外用维生素 E 和微钉辊带来的意想不到的恶性模仿
背景:在迅速扩大的抗衰老市场中,外用维生素 E 因其抗氧化特性而被广泛使用。维生素 E 引起的皮肤反应非常罕见,而且很难诊断:我们报告了一例独特的病例:一名 46 岁的女性在使用微钉滚筒局部涂抹维生素 E 油后,下巴出现了严重的皮肤炎症性病变。临床检查发现了一个易碎和发霉的肿块,因怀疑是恶性肿瘤而进行了活检。病理检查排除了恶性肿瘤的可能性,发现慢性炎症伴有黄疽样特征:结果:经过 18 个月的凯纳洛注射治疗,病变明显好转。疤痕切除术进一步改善了病变的外观:本病例凸显了维生素 E 皮肤反应的罕见性和临床多样性,以及模仿恶性肿瘤的可能性。
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来源期刊
CiteScore
7.00
自引率
6.90%
发文量
278
审稿时长
1.6 months
期刊介绍: Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.
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