Limb Salvage Surgery in Pediatric Patients with Osteosarcoma.

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI:10.12865/CHSJ.50.03.03
Ștefan Adrian Niculescu, Alexandru Florian Grecu, Cristian Gheonea, Dan Cristian Grecu
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Abstract

Osteosarcoma, although rare, is acknowledged as the most common primary bone tumor in children and adolescents. Osteosarcoma is a highly malignant osteogenic tumor that can develop in any bone, but commonly develops at the metaphysis of long bones. The positive diagnosis of osteosarcoma is based on the pathology exam, since there are no other specific diagnostic tools, and the patients with osteosarcoma are typically treated by a multidisciplinary team of specialists. The mainstream for the surgical treatment of limb osteosarcoma is the limb salvage surgery, whenever this approach does not compromise the oncological outcomes. A large spectrum of reconstructive surgical procedures is used in various centers, and to date there is no large consensus on recommending one over another. It is often that the practitioner has to decide whether the final impact on the quality of life of the child undergoing endoprosthetic replacement or osteoarticular allograft is better with the subsequent inequality of the length of the limb or the radical approach by amputation is better. Special consideration has to be given on the aspects of psychosocial wellbeing of the patients following the initial surgical intervention.

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骨肉瘤小儿患者的肢体救治手术
骨肉瘤虽然罕见,但却是儿童和青少年最常见的原发性骨肿瘤。骨肉瘤是一种高度恶性的成骨性肿瘤,可发生于任何骨骼,但常见于长骨的干骺端。由于没有其他特异性诊断工具,骨肉瘤的阳性诊断以病理检查为基础,骨肉瘤患者通常由多学科专家团队进行治疗。肢体骨肉瘤手术治疗的主流是肢体挽救手术,只要这种方法不影响肿瘤治疗效果。各中心采用的重建外科手术种类繁多,但至今仍未就推荐哪种手术方法达成广泛共识。通常情况下,医生必须决定,接受假体置换术或骨关节异体移植术的患儿最终的生活质量是否会因随后的肢体长度不等而受到更好的影响,还是截肢这种根治性方法更好。在最初的手术干预后,必须特别考虑患者的社会心理健康。
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