[Obstetric-gynecological and social factors for the development of cervical intraepithelial neoplasia].

José Alfredo Villanueva-Duque, Isis Carolina Castro-Valdés, Nancy García-Cervantes
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Abstract

Background: Cervical intraepithelial neoplasia (CIN) precedes cervical cancer and it is associated with risk factors that can be identified in the population, which contribute to timely diagnosis and treatment.

Objective: To identify associated risk factors for the development of CIN in women attended at the first level of care.

Material and methods: A cross-sectional and retrospective study was conducted in women in the 2020-2022 period. Frequencies and means were obtained. For the differences, chi-squared and Student's t were used. Odds ratios (OR) were obtained to assess the risk.

Results: ORs were determined in the group of women with CIN II/CIN III, obtaining risks of almost twice the risk factors analyzed compared to the CIN I group, which had the same factors. When analyzed by age groups < or > 40 years, significant associations were determined in the factors of parity, first cytology in life and positive for smoking. In the group < 40 years and with CIN II/III significant risks were determined in age at first pregnancy < 18 (OR 8.33), first cytology in life (OR 3.77), positive for smoking (OR 3.0), sexual intercourse initiation (SII) before 18 years of age (OR 3.1) and parity (OR 1.3).

Conclusions: According to the results obtained, sexual and reproductive behavioral factors are of high risk for the development of CIN.

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[宫颈上皮内瘤变的妇产科和社会因素]。
背景:宫颈上皮内瘤变(CIN)发生于宫颈癌之前,与人群中可识别的风险因素有关,有助于及时诊断和治疗:材料与方法:一项横断面回顾性研究:材料和方法:对 2020-2022 年期间的妇女进行了一项横断面回顾性研究。获得了频率和平均值。差异采用卡方和学生 t。得出的比率(OR)用于评估风险:CINⅡ/CINⅢ妇女组的OR值为分析的风险因素的近两倍,而CINⅠ组的风险因素相同。如果按年龄组(小于或大于 40 岁)进行分析,则会发现奇偶校验、人生中第一次细胞学检查和吸烟呈阳性等因素有显著关联。在年龄小于 40 岁和 CIN II/III 组中,首次怀孕年龄小于 18 岁(OR 8.33)、人生中首次细胞学检查(OR 3.77)、吸烟(OR 3.0)、18 岁前开始性交(SII)(OR 3.1)和奇偶校验(OR 1.3)均有显著风险:根据研究结果,性行为和生殖行为因素是 CIN 的高危因素。
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