Febe Smits, Kaz Groen, Mark-David Levin, Claudia A M Stege, Roel van Kampen, Ellen van der Spek, Yavuz M Bilgin, Noortje Thielen, Inger Nijhof, Inge Ludwig, Esther G M de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane Vekemans, Nazik Durdu-Rayman, Nicole C H P de Graauw, Maarten R Seefat, Niels W C J van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
{"title":"Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma.","authors":"Febe Smits, Kaz Groen, Mark-David Levin, Claudia A M Stege, Roel van Kampen, Ellen van der Spek, Yavuz M Bilgin, Noortje Thielen, Inger Nijhof, Inge Ludwig, Esther G M de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane Vekemans, Nazik Durdu-Rayman, Nicole C H P de Graauw, Maarten R Seefat, Niels W C J van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman","doi":"10.1182/blood.2024025868","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>The level of frailty, according to the International Myeloma Working Group frailty index, is highly dynamic during antimyeloma treatment. Dynamic frailty assessment improved the prediction of survival and early mortality compared with the prognostic value of static frailty level at baseline.</p>","PeriodicalId":9102,"journal":{"name":"Blood","volume":" ","pages":"543-546"},"PeriodicalIF":21.0000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Blood","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1182/blood.2024025868","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: The level of frailty, according to the International Myeloma Working Group frailty index, is highly dynamic during antimyeloma treatment. Dynamic frailty assessment improved the prediction of survival and early mortality compared with the prognostic value of static frailty level at baseline.
期刊介绍:
Blood, the official journal of the American Society of Hematology, published online and in print, provides an international forum for the publication of original articles describing basic laboratory, translational, and clinical investigations in hematology. Primary research articles will be published under the following scientific categories: Clinical Trials and Observations; Gene Therapy; Hematopoiesis and Stem Cells; Immunobiology and Immunotherapy scope; Myeloid Neoplasia; Lymphoid Neoplasia; Phagocytes, Granulocytes and Myelopoiesis; Platelets and Thrombopoiesis; Red Cells, Iron and Erythropoiesis; Thrombosis and Hemostasis; Transfusion Medicine; Transplantation; and Vascular Biology. Papers can be listed under more than one category as appropriate.