A new uterine endometrium preservation hysteroscopic myomectomy: Introduction of improved procedures and a retrospective analysis of 94 cases

Wataru Isono , Masanori Maruyama
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Abstract

Objective

To reduce the damage of uterine endometrium caused during hysteroscopic myomectomy (HM) for reproductive aged patients, a new uterine endometrium preservation hysteroscopic myomectomy (UEP-HM) has been developed. In this study, we introduced this technique with comparing to the conventional hysteroscopic myomectomy (C-HM).

Study Design

The data from 94 patients aged 42 or younger who underwent HM (38 cases with UEP-HM and 56 cases with C-HM) for treating single Type 1 or Type 2 submucosal leiomyoma (SL) were analysed retrospectively for comparing the characteristics of both patient and target SL. In this process, we defined the operation time 60 min or over as the longtime operation (LTO) and the SM sized 3 cm or over as the large submucosal leiomyoma (LSL) for detecting the influential factors, including this procedure, on the difficulty of HM. For assisting the prediction of operation time (OT), we investigated the relationship between the OT and the cube of average diameter (AD) of target SL referring with some past reports.

Results

Although when comparing UEP and control groups, parity, AD, the number of patients with Type 2 SL, OT, and the number of infertile patients showed significant difference, in the multivariate analysis only LSL showed the significant influence on the possibility of LTO. Next, we compared OT/Cube of AD, which calculated by dividing OT by the cube of AD for evaluating OT from the target SL size and confirmed that there was no difference in those 2 groups (3.7 ± 3.0 (95 %CI: 0.9 - 13.3, n = 38) vs. 3.9 ± 3.2 (95 %CI: 0.4 - 17.3, n = 56), p = 0.79).

Conclusions

The new UEP-HM can become an alternative method of C-HM without procedure-specific difficulty. In the future, to investigate the prognosis of this procedure, more patients and further analyses should be accumulated.
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新型子宫内膜保留宫腔镜子宫肌瘤剔除术:改进程序介绍和 94 例病例的回顾性分析
目的 为了减少宫腔镜子宫肌瘤剔除术(HM)对育龄患者子宫内膜的损伤,一种新的子宫内膜保留宫腔镜子宫肌瘤剔除术(UEP-HM)应运而生。研究设计回顾性分析了94例年龄在42岁或以下、接受宫腔镜子宫肌瘤剔除术(UEP-HM 38例,C-HM 56例)治疗单个1型或2型粘膜下子宫肌瘤(SL)的患者数据,以比较患者和目标SL的特征。在这一过程中,我们将手术时间在 60 分钟或以上的手术定义为长时间手术(LTO),将 3 厘米或以上的粘膜下大肌瘤定义为粘膜下大肌瘤(LSL),以检测包括该手术在内的影响 HM 难度的因素。为了帮助预测手术时间(OT),我们参考过去的一些报道,研究了 OT 与目标 SL 平均直径立方值(AD)之间的关系。结果虽然在比较 UEP 组和对照组时,奇偶数、AD、2 型 SL 患者人数、OT 和不孕患者人数均有显著差异,但在多变量分析中,只有 LSL 对 LTO 的可能性有显著影响。接下来,我们比较了OT/AD立方,即用OT除以AD立方来评估目标SL尺寸的OT,结果证实这两组没有差异(3.7 ± 3.0 (95 %CI: 0.9 - 13.3, n = 38) vs. 3.9 ± 3.2 (95 %CI: 0.4 - 17.3, n = 56), p = 0.79)。结论:新的 UEP-HM 可成为 C-HM 的替代方法,且无手术特异性困难。未来,为研究该手术的预后,应积累更多患者并进行进一步分析。
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来源期刊
CiteScore
2.20
自引率
0.00%
发文量
31
审稿时长
58 days
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