IoT based healthcare system using fractional dung beetle optimization enabled deep learning for breast cancer classification

IF 2.6 4区 生物学 Q2 BIOLOGY Computational Biology and Chemistry Pub Date : 2024-11-10 DOI:10.1016/j.compbiolchem.2024.108277
Vaddadi Vasudha Rani , G. Vasavi , P. Mano Paul , K. Sandhya Rani
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Abstract

Breast cancer classification plays a crucial role in healthcare, especially in the diagnosis and monitoring of patients. Traditional methods for classifying breast cancer based on histopathological images often suffer from limited accuracy, which can hinder early detection and treatment. Hence, this paper devises a novel Internet of Things (IoT) based healthcare system using SqueezeNet_Fractional Dung Beetle Optimization (Squeeze_FDBO) for breast cancer detection. Initially, IoT network is simulated, and routing of the histopathological images to the Base Station (BS) is established utilizing FDBO, which is obtained by combining Dung Beetle Optimizer (DBO), and the Fractional Calculus (FC). At BS, breast cancer classification is done, where input is first processed by a bilateral filter. Then, blood cell segmentation is effectuated using LadderNet, and then, feature extraction is performed. Finally, the multigrade classification of breast cancer is executed utilizing SqueezeNet tuned by FDBO. The efficiency of Squeeze_FDBO is validated using various performance measures, and it is found to record an accuracy of 0.919, sensitivity of 0.913, specificity of 0.923, Negative Predictive Value (NPV) of 0.920, and Positive Predictive Value (PPV) of 0.908, and a better routing performance with energy of 0.405 J, distance of 6.901 m, and delay of 0.650mS.
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基于物联网的医疗保健系统利用分数蜣螂优化深度学习进行乳腺癌分类
乳腺癌分类在医疗保健中发挥着至关重要的作用,尤其是在诊断和监测患者方面。传统的基于组织病理学图像的乳腺癌分类方法往往准确性有限,这可能会阻碍早期检测和治疗。因此,本文利用 SqueezeNet_Fractional Dung Beetle Optimization(Squeeze_FDBO)设计了一种基于物联网(IoT)的新型医疗系统,用于乳腺癌检测。首先,模拟物联网网络,并利用分数蜣螂优化器(DBO)和分数微积分(FC)建立组织病理学图像到基站(BS)的路由。在 BS 上进行乳腺癌分类,输入首先经过双边滤波器处理。然后,使用 LadderNet 进行血细胞分割,再进行特征提取。最后,利用经 FDBO 调整的 SqueezeNet 对乳腺癌进行多级分类。使用各种性能指标验证了 Squeeze_FDBO 的效率,发现它的准确率为 0.919,灵敏度为 0.913,特异性为 0.923,负预测值(NPV)为 0.920,正预测值(PPV)为 0.908,路由性能更好,能量为 0.405 J,距离为 6.901 m,延迟为 0.650mS。
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来源期刊
Computational Biology and Chemistry
Computational Biology and Chemistry 生物-计算机:跨学科应用
CiteScore
6.10
自引率
3.20%
发文量
142
审稿时长
24 days
期刊介绍: Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered. Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered. Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.
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