The Modern Epidemic of Autoimmunity

IF 2.4 4区 医学 Q2 RHEUMATOLOGY International Journal of Rheumatic Diseases Pub Date : 2024-11-25 DOI:10.1111/1756-185X.15426
Jie-Fu Zheng, Yung-Heng Lee, Pui-Ying Leong
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Abstract

Autoimmunity occurs when the immune system mistakenly attacks the body, but the presence of autoantibodies, such as antinuclear antibodies (ANAs), does not always lead to autoimmune diseases. Globally, autoimmunity is on the rise, influenced by socioeconomic factors, environmental exposure, diet, and stress. Climate change and pollution further exacerbate risks. The COVID-19 pandemic has worsened the issue, with unvaccinated individuals showing higher rates of autoimmune conditions postinfection. Preventive strategies, including healthy diets, stress management, and vaccination, are crucial in combating this growing epidemic. Collaboration between individuals, healthcare providers, and policymakers is critical to mitigate the rise in autoimmune disorders and enhance public health.

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现代自体免疫流行病
自身免疫是指免疫系统错误地攻击人体,但自身抗体(如抗核抗体(ANA))的存在并不一定会导致自身免疫性疾病。在全球范围内,受社会经济因素、环境暴露、饮食和压力的影响,自身免疫性疾病呈上升趋势。气候变化和污染进一步加剧了风险。COVID-19 大流行使这一问题更加严重,未接种疫苗的人在感染后出现自身免疫疾病的比例更高。包括健康饮食、压力管理和疫苗接种在内的预防策略对于应对这一日益严重的流行病至关重要。个人、医疗保健提供者和政策制定者之间的合作对于缓解自身免疫性疾病的增加和提高公共卫生水平至关重要。
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来源期刊
CiteScore
3.70
自引率
4.00%
发文量
362
审稿时长
1 months
期刊介绍: The International Journal of Rheumatic Diseases (formerly APLAR Journal of Rheumatology) is the official journal of the Asia Pacific League of Associations for Rheumatology. The Journal accepts original articles on clinical or experimental research pertinent to the rheumatic diseases, work on connective tissue diseases and other immune and allergic disorders. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer reviewed by two anonymous reviewers and the Editor.
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