Painful Legs and Moving Toes Syndrome: Case Report and Review.

IF 3.2 Q2 CLINICAL NEUROLOGY Neurology International Pub Date : 2024-11-04 DOI:10.3390/neurolint16060102
Mihael Tsalta-Mladenov, Vladina Dimitrova, Silva Andonova
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Abstract

Introduction: Painful legs and moving toes (PLMT) syndrome is a rare movement disorder characterized by defuse lower limb neuropathic pain and spontaneous abnormal, involuntary toe movements.

Objective: The objective was to present a rare case of PLMT syndrome with a triggering area in an adult patient due to multilevel discogenic pathology, to make a thorough review of this disorder and to provide a practical approach to its management.

Case presentation: A 59-years-old male was admitted to the neurology ward with symptoms of defuse pain in the lower-back and the right leg accompanied by involuntary movements for the right toes intensified by tactile stimulation in the right upper thigh. Magnetic resonance imaging (MRI) revealed a multilevel discogenic pathology of the lumbar and cervical spine, with myelopathy at C5-C7 level. A medication with Pregabalin 300 mg/daily significantly improved both the abnormal toe movements and the leg pain. The clinical effect was constant during the 90-day follow-up without any adverse effects.

Conclusion: Painful legs and moving toes (PLMT) is a condition that greatly affects the quality of life of patients, but which still remains less known by clinicians. Spontaneous resolution is rare, and oral medications are the first-line treatment. Pregabalin is a safe and effective treatment option for PLMT that should be considered early for the management of this condition. Other medication interventions, such as botulinum toxin injections, spinal blockade, or non-pharmacological treatment options like spinal cord stimulation, and surgical decompressions, are also recommended when the conservative treatment is ineffective in well-selected patients.

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腿痛和脚趾移动综合征:病例报告与回顾
简介:疼痛性腿和脚趾运动综合征(PLMT)是一种罕见的运动障碍疾病,其特征是下肢神经病理性疼痛缓解和自发性异常不自主脚趾运动:疼痛性腿和脚趾运动综合征(PLMT)是一种罕见的运动障碍,其特征是下肢神经病理性疼痛和自发性异常、不自主脚趾运动:目的:介绍一例罕见的成年患者因多层次椎间盘病变导致的具有触发区的 PLMT 综合征,对该疾病进行全面回顾,并提供实用的治疗方法:一名 59 岁的男性因下腰和右腿疼痛加剧,伴有右脚趾不自主运动,右大腿上部触觉刺激加剧的症状被送入神经内科病房。磁共振成像(MRI)显示,腰椎和颈椎存在多级椎间盘病变,C5-C7水平存在脊髓病变。服用普瑞巴林 300 毫克/天的药物后,脚趾异常运动和腿部疼痛都得到了明显改善。临床效果在90天的随访中保持不变,且无任何不良反应:结论:腿痛和脚趾移动(PLMT)是一种严重影响患者生活质量的疾病,但临床医生对这种疾病的了解仍然较少。自发缓解的情况很少见,口服药物是一线治疗方法。普瑞巴林是一种安全有效的 PLMT 治疗选择,应尽早考虑用于治疗这种疾病。当保守治疗无效时,也建议对经过严格筛选的患者采取其他药物干预措施,如注射肉毒杆菌毒素、脊髓阻滞或脊髓刺激、手术减压等非药物治疗方案。
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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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