[Breast Cancer In Women: Prognostic Factors And Survival In The General Surgery Department At The Gabriel Touré University Hospital, Bamako].

Abstract

Objectives: The aim of this work was to study the prognostic factors of breast cancer and their correlation with survival in women in the General Surgery Department of the Gabriel Touré CHU in Bamako.

Materials and methods: This was a cohort study from January 2020 to December 2022, a period of 36 months.

Results: A total of 67 patients were registered. The mean age was 47.6 ±13.3 years; the mean time to consultation was 12.7 ±11.6 months. A breast mass was palpable in 82% of cases; its mean size was 7.18 cm±3,97. It was a non-specific infiltrating ductal carcinoma in 95.52% of cases. SBR grade 3 was found in 32.84%. Advanced stages (III and IV) accounted for 77.61% of cancers. The majority of cancers (50.74%) were triple-negative subtypes. Mastectomy with axillary dissection was performed in 95.52% of patients, with significant lymph node involvement in 35.82% of cases. Targeted therapy was performed in 7.46% of cases. Post-operative follow-up was straightforward in 89.09% of cases. Overall survival was 26.30 months with a median survival of 23.86 months. SBR3 grade and triple-negative subtype were the prognostic factors that significantly influenced survival.

Conclusion: Efficient management of breast cancer requires proper assessment of prognostic factors. Biomolecular factors SBR-EE and triple-negative had a strong correlation with survival.