[Evaluation Of Fibroscan® In The Prediction Of Esophageal Varices In Cirrhotic Patients Followed At Cocody'shospital].

Abstract

Objective: To evaluate the prediction of esophageal varices by SEF measured by fibroscan® in cirrhotic patients followed at Cocody CHU.

Method: This was a cross-sectional study conducted at HGE at Cocody CHU for 5 years. Included records of compensated cirrhotics followed at HGE. The judgment criteria were the SEF and FOGD. R software version 4.2.1 was used for analysis and the khi 2 test or the exact Fischer test for the variables. To evaluate the diagnostic performance of the SEF for VO diagnosis, were compared; patients with and without VO on the one hand, and patients with and without large VO on the other hand. The respective predictive optimal OV and large OV diagnostic thresholds were determined from a ROC curve. The diagnostic performance of these optimal thresholds was evaluated by their Se, Sp, VPP, and VPN, RV+ and RV-.

Results: 75 patients were retained. The average age was 45.4 14.1 years. Half had OVs. The threshold for predicting the presence of VO was 13.7 kPa and for large VO was 17.1 kPa with an Se of 92% [79 ;98] and 75% [55 ;89]; an Sp of 84% [68;94] and 90% [55;99] respectively; an VPP of 85% [71; 97] and 96% [74; 98] and a VPN of 91% [77;97] and 56% [35;98] respectively with an accuracy (AUROC) of 92% [85; 98] (p<0.001) and 76% [66; 87] (p<0.001).

Conclusion: The liver elasticity score measured by fibroscan® has a good non-invasive diagnostic performance of esophageal varices and mean diagnostic performance of large varice at the respective thresholds of 13.7 and 17.1kPa.