Personality functioning in bipolar 1 disorder and borderline personality disorder.

IF 3.4 2区 医学 Q2 PSYCHIATRY BMC Psychiatry Pub Date : 2024-11-25 DOI:10.1186/s12888-024-06297-8
Karin Feichtinger, Clarissa Laczkovics, Johanna Alexopoulos, Maria Gruber, Miriam Klauser, Karoline Parth, Antonia Wininger, Michael Ossege, Josef Baumgartner, Stephan Doering, Victor Blüml
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Abstract

Background: Differentiation of borderline personality disorder (BPD) and bipolar I disorder (BD) has been challenging. The assessment of shared symptoms in the context of the overall personality functioning, the patient's sense of self, and the quality of his object (interpersonal) relations is proposed to be valuable for the differential diagnosis of these disorders.

Methods: We empirically investigated the level of personality organization (PO), identity integration, and quality of object relations in patients suffering from BD or BPD using the Structured Interview of Personality Organization (STIPO) and the Level of Personality Functioning Scale (LPFS) in 34 BPD and 28 BD patients as well as 27 healthy control persons. Group comparisons and a logistic regression model were calculated to analyze group differences.

Results: The BPD group showed significantly greater impairment in several domains of personality functioning, namely "identity", and "self- and other-directed aggression", while showing lower impairment in "moral values". The overall level of PO in the BPD group was significantly lower when excluding not only BPD but any personality disorder (PD) in the BD sample. Severity of impaired personality structure had a major impact on symptom load independent of the main diagnosis BD or BPD.

Conclusions: Our data show greater impairment in personality functioning in BPD than in BD patients. BD patients present with varying levels of PO, whereas in BPD severe deficits in PO are pathognomonic. The level of PO has a significant impact on symptom severity in both BD and BPD patients. Therefore, careful assessment of PO should be considered for differential diagnosis and adequate treatment planning.

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双相情感障碍和边缘型人格障碍的人格功能。
背景:边缘型人格障碍(BPD)和双相情感障碍(BD)的鉴别一直是个难题。在整体人格功能、患者的自我意识及其客体(人际)关系质量的背景下对共同症状进行评估,对于这些障碍的鉴别诊断很有价值:我们使用人格组织结构访谈(STIPO)和人格功能水平量表(LPFS)对34名BPD和28名BD患者以及27名健康对照者进行了实证调查,以了解BD或BPD患者的人格组织(PO)水平、身份整合和客体关系质量。研究人员计算了组间比较和逻辑回归模型,以分析组间差异:结果:BPD 组在 "身份认同"、"自我和他人导向的攻击性 "等几个人格功能领域的障碍程度明显更高,而在 "道德价值观 "领域的障碍程度较低。如果将 BD 样本中的 BPD 和任何人格障碍(PD)排除在外,BPD 组的 PO 总体水平明显更低。人格结构受损的严重程度对症状负荷有重大影响,与主要诊断为BD还是BPD无关:我们的数据显示,BPD 患者的人格功能受损程度比 BD 患者严重。BD患者表现出不同程度的PO,而在BPD患者中,严重的PO缺陷是病征。PO水平对BD和BPD患者的症状严重程度都有显著影响。因此,在进行鉴别诊断和制定适当的治疗计划时,应考虑对 PO 进行仔细评估。
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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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