Plasma cell type Castleman's disease of lacrimal gland: a case report and literature review.

IF 1.7 4区 医学 Q3 OPHTHALMOLOGY BMC Ophthalmology Pub Date : 2024-11-25 DOI:10.1186/s12886-024-03775-1
Liangyuan Xu, Jing Li, Xiaolin Xu, Tingting Ren, Jianmin Ma
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Abstract

Background: Orbital Castleman's disease is a rare benign lymphoproliferative disorder of extranodal origin.

Case presentation: A 72-year-old man presented with bilateral upper eyelid swelling. Radiology revealed enlarged lacrimal glands in both eyes. Castleman's disease (plasma cell type) was confirmed by histo-immunochemical examinations after excision of the left orbital mass. No extraorbital involvement was found in systemic evaluation. Postoperatively, corticosteroid therapy was given. After 1 year of follow-up, there was no recurrence in the left orbit, and the swelling of the right eyelid was improved.

Conclusions: Here, we report a case of orbital Castleman's disease involving the lacrimal gland bilaterally and summarize previously reported cases. For bilateral orbital masses, the possibility of Castleman's disease should be considered. Before the diagnosis, it is necessary to fully distinguish from other diseases such as IgG4-related eye diseases.

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泪腺浆细胞型卡斯特曼病:病例报告和文献综述。
背景:眼眶卡斯特曼病是一种罕见的良性淋巴组织增生性疾病:眼眶卡斯尔曼氏病是一种罕见的结节外源性良性淋巴增生性疾病:一名 72 岁的男子因双侧上眼睑肿胀就诊。放射学检查显示双眼泪腺肿大。切除左眼眶肿块后,通过组织免疫化学检查确诊为卡斯特曼病(浆细胞型)。全身评估未发现眶外病变。术后给予了皮质类固醇治疗。随访一年后,左眼眶未见复发,右眼睑肿胀也有所改善:在此,我们报告了一例双侧泪腺受累的眼眶卡斯特曼氏病病例,并对之前报告的病例进行了总结。对于双侧眼眶肿块,应考虑卡氏病的可能性。在诊断前,有必要与其他疾病(如 IgG4 相关眼病)进行充分鉴别。
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来源期刊
BMC Ophthalmology
BMC Ophthalmology OPHTHALMOLOGY-
CiteScore
3.40
自引率
5.00%
发文量
441
审稿时长
6-12 weeks
期刊介绍: BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
期刊最新文献
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