Nutrigenomics and neurological disorders: exploring diet-brain interactions for cognitive health.

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Neurogenetics Pub Date : 2024-11-26 DOI:10.1007/s10048-024-00791-7
Atifa Waheed, Maliha Ghaffar, Samavia Mustafa, Anam Abbas, Sana Khan, Ahmad Waheed, Hina Naz
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Abstract

This review article investigates the intricate relationship between nutrigenomics and neurological disorders, highlighting how genetic variations affect an individual's response to nutrients. The study delves into the role of diet-related oxidative stress and the gut-brain axis in the progression and management of brain disorders such as Parkinson's disease, Alzheimer's disease, epilepsy, stroke, migraines, and depression. The review encompasses various clinical trials and introduces new trends and techniques, including omics and artificial intelligence, in identifying and managing neurological disorders. The main findings emphasize that personalized diet recommendations, tailored to an individual's genetic makeup, can significantly improve cognitive health and manage neurological conditions. The study concludes that further research in the field of nutrigenomics is essential to advancing personalized nutrition strategies for better neurological functioning, ultimately linking diet, genes, and brain health.

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营养基因组学与神经系统疾病:探索饮食与大脑的相互作用,促进认知健康。
这篇综述文章探讨了营养基因组学与神经系统疾病之间错综复杂的关系,强调了基因变异如何影响个体对营养素的反应。研究深入探讨了与饮食相关的氧化应激和肠脑轴在帕金森病、阿尔茨海默病、癫痫、中风、偏头痛和抑郁症等脑部疾病的进展和管理中的作用。综述涵盖了各种临床试验,并介绍了在识别和管理神经系统疾病方面的新趋势和新技术,包括全息图学和人工智能。主要研究结果强调,根据个人基因构成量身定制的个性化饮食建议可以显著改善认知健康和管理神经系统疾病。研究得出结论,要想推进个性化营养策略以改善神经功能,最终将饮食、基因和大脑健康联系起来,营养基因组学领域的进一步研究至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neurogenetics
Neurogenetics 医学-临床神经学
CiteScore
3.90
自引率
0.00%
发文量
24
审稿时长
6 months
期刊介绍: Neurogenetics publishes findings that contribute to a better understanding of the genetic basis of normal and abnormal function of the nervous system. Neurogenetic disorders are the main focus of the journal. Neurogenetics therefore includes findings in humans and other organisms that help understand neurological disease mechanisms and publishes papers from many different fields such as biophysics, cell biology, human genetics, neuroanatomy, neurochemistry, neurology, neuropathology, neurosurgery and psychiatry. All papers submitted to Neurogenetics should be of sufficient immediate importance to justify urgent publication. They should present new scientific results. Data merely confirming previously published findings are not acceptable.
期刊最新文献
Retraction Note: Impact of flexible assertive community treatment model (FACT) on community rehabilitation of schizophrenia in Southern China. Genetic and expressional insights into the association of TRAPPC10 variants with neurodevelopmental disorders. Correction to: Gene-gene interaction network analysis indicates CNTN2 is a candidate gene for idiopathic generalized epilepsy. Phenotypic variability in progressive encephalopathy with brain atrophy and thin corpus callosum: insights from two families. The molecular mechanism of nitric oxide in memory consolidation and its role in the pathogenesis of memory-related disorders.
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