Exosomes in esophageal cancer: function and therapeutic prospects.

IF 2.8 4区 医学 Q2 ONCOLOGY Medical Oncology Pub Date : 2024-11-27 DOI:10.1007/s12032-024-02543-x
Chong Wang, Zhi-Zhou Shi
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Abstract

Esophageal cancer (EC) is one of the most common malignant tumors worldwide. Exosomes are a type of extracellular vesicles produced by eukaryotic cells and present in all body fluids. Recent studies have revealed that exosomes can be used as a tool for cell signaling and have great potential in cancer diagnosis and treatment strategies. This article reviews the research progress of exosomes in EC in recent years, mainly including the mechanism of action, diagnostic markers, therapeutic targets, and drug carriers. The challenges faced are discussed to provide guidelines for further research in future.

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食管癌中的外泌体:功能和治疗前景。
食管癌(EC)是全球最常见的恶性肿瘤之一。外泌体是真核细胞产生的一种细胞外囊泡,存在于所有体液中。最新研究发现,外泌体可作为细胞信号转导的工具,在癌症诊断和治疗策略中具有巨大潜力。本文回顾了近年来外泌体在EC中的研究进展,主要包括作用机制、诊断标志物、治疗靶点和药物载体。文章还讨论了所面临的挑战,为今后的进一步研究提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical Oncology
Medical Oncology 医学-肿瘤学
CiteScore
4.20
自引率
2.90%
发文量
259
审稿时长
1.4 months
期刊介绍: Medical Oncology (MO) communicates the results of clinical and experimental research in oncology and hematology, particularly experimental therapeutics within the fields of immunotherapy and chemotherapy. It also provides state-of-the-art reviews on clinical and experimental therapies. Topics covered include immunobiology, pathogenesis, and treatment of malignant tumors.
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