A snapshot of biomanufacturing and the need for enabling research infrastructure.

Abstract

Biomanufacturing is crucial for the bioeconomy, with growing investment and attention from industries and governments. Over recent decades numerous biotech companies have been founded, and policies have increasingly prioritised sustainable production methods. However, translation of biotechnological innovations into industrial applications remains challenging, requiring interdisciplinary research infrastructures (RIs) to address gaps in bioprocess development, scalability, and competitiveness. This opinion examines the current landscape of biomanufacturing and highlights the pivotal role of RIs in supporting these transitions. It also proposes enhanced research interoperability, standardisation, and democratisation through meta-workflows that streamline operations within and between RIs. By improving data sharing, process harmonisation, and scalability, these ecosystems can help to overcome technical and economic barriers in a concerted effort towards sustainable, bio-based global manufacturing.