Mpox Resurgence: A Multifaceted Analysis for Global Preparedness.

IF 3.5 3区 医学 Q2 VIROLOGY Viruses-Basel Pub Date : 2024-11-05 DOI:10.3390/v16111737
Fatouma Mohamed Abdoul-Latif, Ayoub Ainane, Houda Mohamed, Ali Merito Ali, Ibrahim Houmed Aboubaker, Pannaga Pavan Jutur, Tarik Ainane
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Abstract

This study provides an in-depth analysis of mpox, encompassing its history, characteristics, epidemiology, diagnostics, treatment options, and the ongoing evolution of the virus and its transmission dynamics. Mpox, though once successfully eradicated, has re-emerged with new modes of transmission and a broader host range. Genomic analyses have revealed the virus's adaptability, posing challenges for diagnostics and vaccine efficacy. The epidemiology has shifted from sporadic zoonotic transmission in rural Africa to a significant presence in urban areas, particularly impacting high-risk populations. Advancements in diagnostics and therapeutics offer hope, but challenges persist. This work underscores the critical need for enhanced surveillance, vaccination strategies, and continued research to bolster global health systems and preparedness for future outbreaks.

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麻疹病毒卷土重来:全球备战的多层面分析。
本研究对水痘进行了深入分析,包括水痘的历史、特征、流行病学、诊断方法、治疗方案以及病毒的不断演变和传播动态。麻风痘曾一度被成功根除,但现在又以新的传播方式和更广泛的宿主范围重新出现。基因组分析揭示了病毒的适应性,给诊断和疫苗疗效带来了挑战。流行病学已从非洲农村地区的零星人畜共患病传播转变为城市地区的大量存在,特别是对高危人群的影响。诊断学和治疗学的进步带来了希望,但挑战依然存在。这项工作强调了加强监测、疫苗接种策略和持续研究的迫切需要,以加强全球卫生系统,为未来的疫情爆发做好准备。
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来源期刊
Viruses-Basel
Viruses-Basel VIROLOGY-
CiteScore
7.30
自引率
12.80%
发文量
2445
审稿时长
1 months
期刊介绍: Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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