Low Skeletal Muscle Mass: A Strong Predictive Factor for Surgical Complications After Free Forearm Flap Reconstruction in Oral Cancer Patients.

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2024-11-27 DOI:10.1002/hed.28014

E Ansari, N Carrillo Minulina, M A van Beers, R J J van Es, F J Dieleman, A J W P Rosenberg, L M Janssen, W W Braunius, E M Van Cann, R de Bree

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Abstract

Background: Low skeletal muscle mass (SMM) is a predictive factor for complications in patients undergoing major head and neck cancer surgery. This study aims to identify the predictive value of low SMM for postoperative complications in patients who underwent free forearm flap (FAFF) reconstructions after oral cancer resections.

Methods: A retrospective study was performed with all patients who underwent FFAF between 2003 and 2020 for an oral cavity reconstruction after cancer ablation. Free flap related, any postoperative complications and hospital stay were investigated.

Results: Low SMM was associated with an increased risk of free flap associated complications (OR 2.14; 95% CI 1.02-4.39, p = 0.029). Low SMM was associated with severe complications (Clavien-Dindo ≥ III) (OR 1.46; 95% CI 1.20-2.09, p = 0.02).

Conclusions: Low SMM is a strong predictive factor for free flap related surgical complications in patients undergoing FAFF reconstruction after resection of oral cancer.

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骨骼肌质量低：口腔癌患者游离前臂皮瓣重建术后手术并发症的强预测因素

背景：低骨骼肌质量（SMM）是头颈部癌症大手术患者出现并发症的一个预测因素。本研究旨在确定低骨骼肌质量对口腔癌切除术后接受游离前臂皮瓣（FAFF）重建患者术后并发症的预测价值：对 2003 年至 2020 年期间所有接受游离前臂皮瓣（FAFF）手术的癌症消融术后口腔重建患者进行回顾性研究。研究调查了游离皮瓣相关情况、术后并发症和住院时间：低 SMM 与游离皮瓣相关并发症的风险增加有关（OR 2.14；95% CI 1.02-4.39，P = 0.029）。低 SMM 与严重并发症（Clavien-Dindo ≥ III）相关（OR 1.46; 95% CI 1.20-2.09, p = 0.02）：低SMM是口腔癌切除术后接受FAFF重建的患者出现游离皮瓣相关手术并发症的一个强有力的预测因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.