The Successful Treatment of Multi-Resistant Colonized Burns with Large-Area Atmospheric Cold Plasma Therapy and Dermis Substitute Matrix-A Case Report.

IF 1 Q4 CRITICAL CARE MEDICINE European burn journal Pub Date : 2024-08-26 DOI:10.3390/ebj5030025
Moritz R Milewski, Frederik Schlottmann, Vincent März, Thorben Dieck, Peter M Vogt
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Abstract

The treatment of severe burn injuries, which occur particularly in the context of armed conflicts, is based on a multimodal treatment concept. In addition to complex intensive care therapy, the surgical reconstruction options of plastic surgery and typical antiseptic wound treatment are the main focuses. In recent years, atmospheric cold plasma therapy (ACPT) has also become established for topical, antiseptic wound treatment and for the optimization of re-epithelialization. This case report shows a successful treatment of extensive burn injuries using dermal skin substitute matrix and topical treatment with a large-area cold plasma device to control multi-resistant pathogen colonization. This case report illustrates the importance of ACPT in burn surgery. However, larger case series and randomized controlled trials in specialized centers are needed to assess its place in future clinical practice.

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大面积常压冷等离子体疗法和真皮替代基质成功治疗多发性菌落性烧伤--病例报告。
严重烧伤(尤其是在武装冲突中发生的烧伤)的治疗基于多模式治疗理念。除了复杂的重症监护治疗外,整形外科的手术重建方案和典型的伤口消毒处理也是治疗的重点。近年来,常压冷等离子体疗法(ACPT)也开始用于局部伤口防腐治疗和优化再上皮化。本病例报告显示,使用真皮皮肤替代基质和大面积冷等离子设备进行局部治疗,成功治疗了大面积烧伤,控制了多重耐药病原体的定植。该病例报告说明了 ACPT 在烧伤手术中的重要性。不过,还需要在专业中心进行更大规模的病例系列研究和随机对照试验,以评估其在未来临床实践中的地位。
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