Mimicking fluorophores from nature to generate artificial fluorescent proteins and biosensors

IF 19.2 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Nature chemistry Pub Date : 2024-11-28 DOI:10.1038/s41557-024-01677-9
Chia-Heng Hsiung, Xin Zhang
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Abstract

The miniaturization and redesigning of proteins to bear fluorescence signals can broaden their scope for potential applications. Now, one can construct a range of compact artificial fluorescent proteins and develop protein biosensors by genetically encoding a natural fluorescent protein chromophore analogue.

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模仿自然界的荧光团生成人工荧光蛋白和生物传感器
使蛋白质小型化并重新设计以携带荧光信号,可以扩大其潜在的应用范围。现在,人们可以构建一系列小巧的人造荧光蛋白,并通过基因编码天然荧光蛋白发色团类似物来开发蛋白质生物传感器。
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来源期刊
Nature chemistry
Nature chemistry 化学-化学综合
CiteScore
29.60
自引率
1.40%
发文量
226
审稿时长
1.7 months
期刊介绍: Nature Chemistry is a monthly journal that publishes groundbreaking and significant research in all areas of chemistry. It covers traditional subjects such as analytical, inorganic, organic, and physical chemistry, as well as a wide range of other topics including catalysis, computational and theoretical chemistry, and environmental chemistry. The journal also features interdisciplinary research at the interface of chemistry with biology, materials science, nanotechnology, and physics. Manuscripts detailing such multidisciplinary work are encouraged, as long as the central theme pertains to chemistry. Aside from primary research, Nature Chemistry publishes review articles, news and views, research highlights from other journals, commentaries, book reviews, correspondence, and analysis of the broader chemical landscape. It also addresses crucial issues related to education, funding, policy, intellectual property, and the societal impact of chemistry. Nature Chemistry is dedicated to ensuring the highest standards of original research through a fair and rigorous review process. It offers authors maximum visibility for their papers, access to a broad readership, exceptional copy editing and production standards, rapid publication, and independence from academic societies and other vested interests. Overall, Nature Chemistry aims to be the authoritative voice of the global chemical community.
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