Development of Korean CARcinogen EXposure: occupation-based exposure matrix.

IF 1.8 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Annals Of Work Exposures and Health Pub Date : 2024-11-27 DOI:10.1093/annweh/wxae090

Dong-Hee Koh, Sangjun Choi, Ju-Hyun Park, Sang-Gil Lee, Hwan-Cheol Kim, Inah Kim, Jeehee Min, Yujin Kim, Dong-Uk Park

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Abstract

Objectives: Information systems focusing on occupational carcinogen exposure, whether categorized by industry or occupation, play a pivotal role in the prevention of occupational cancers. Recently, the Korean CARcinogen EXposure (K-CAREX) system was developed to assess carcinogen exposure by industry. However, corresponding information categorized by occupation has yet to be developed. This study aimed to develop an occupation-based exposure matrix for occupational carcinogens as an extension of the K-CAREX framework.

Methods: The Work Environment Measurement Database (WEMD) and the Special Health Examination Database (SHED) were combined to estimate exposure intensity by occupation. The WEMD supplied exposure levels, whereas the SHED provided occupation information. Additionally, the SHED served as the primary data source for constructing an indicator of exposure prevalence by occupation, utilizing standard occupational classification.

Results: A total of 22 carcinogens were selected for evaluating exposure intensity, and 20 carcinogens were selected for assessing exposure prevalence. Exposure intensity and prevalence were assigned to 156 occupational groups based on these carcinogens. For instance, in terms of welding fume exposure, welders were assigned an exposure intensity rating of 3 and exhibited exposure prevalence of 26%.

Conclusions: Our findings complement the previously developed K-CAREX, which offered an industry-based exposure matrix. The resultant comprehensive K-CAREX, incorporating both industry- and occupation-based matrices, can be utilized for occupational cancer prevention and epidemiological studies.

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制定韩国 CARcinogen EXposure：基于职业的暴露矩阵。

目标：以职业致癌物接触为重点的信息系统，无论是按行业还是按职业分类，在预防职业癌症方面都发挥着关键作用。最近，韩国开发了职业致癌物暴露（K-CAREX）系统，以评估各行业的致癌物暴露情况。然而，按职业分类的相应信息尚未开发出来。本研究旨在开发基于职业的职业致癌物暴露矩阵，作为 K-CAREX 框架的扩展：方法：将工作环境测量数据库（WEMD）和特殊健康检查数据库（SHED）结合起来，按职业估算暴露强度。WEMD 提供暴露水平，而 SHED 提供职业信息。此外，SHED还是利用标准职业分类构建职业暴露流行率指标的主要数据来源：结果：共选择了 22 种致癌物质来评估暴露强度，选择了 20 种致癌物质来评估暴露流行率。根据这些致癌物质，将接触强度和接触流行率分配到 156 个职业组别。例如，在接触焊接烟尘方面，焊工的接触强度被定为 3 级，接触流行率为 26%：我们的研究结果是对之前开发的 K-CAREX 的补充，K-CAREX 提供了基于行业的暴露矩阵。由此产生的综合 K-CAREX，既包括基于行业的矩阵，也包括基于职业的矩阵，可用于职业癌症预防和流行病学研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals Of Work Exposures and Health Medicine-Public Health, Environmental and Occupational Health

CiteScore

4.60

自引率

19.20%

发文量

期刊介绍： About the Journal Annals of Work Exposures and Health is dedicated to presenting advances in exposure science supporting the recognition, quantification, and control of exposures at work, and epidemiological studies on their effects on human health and well-being. A key question we apply to submission is, "Is this paper going to help readers better understand, quantify, and control conditions at work that adversely or positively affect health and well-being?" We are interested in high quality scientific research addressing: the quantification of work exposures, including chemical, biological, physical, biomechanical, and psychosocial, and the elements of work organization giving rise to such exposures; the relationship between these exposures and the acute and chronic health consequences for those exposed and their families and communities; populations at special risk of work-related exposures including women, under-represented minorities, immigrants, and other vulnerable groups such as temporary, contingent and informal sector workers; the effectiveness of interventions addressing exposure and risk including production technologies, work process engineering, and personal protective systems; policies and management approaches to reduce risk and improve health and well-being among workers, their families or communities; methodologies and mechanisms that underlie the quantification and/or control of exposure and risk. There is heavy pressure on space in the journal, and the above interests mean that we do not usually publish papers that simply report local conditions without generalizable results. We are also unlikely to publish reports on human health and well-being without information on the work exposure characteristics giving rise to the effects. We particularly welcome contributions from scientists based in, or addressing conditions in, developing economies that fall within the above scope.