Current Status and Development of Rat DCD Renal Transplantation Model.

Transplantation proceedings Pub Date : 2024-12-01 Epub Date: 2024-11-27 DOI:10.1016/j.transproceed.2024.11.004
Shang Xu, Zhilong Liu, Xinning Wang
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Abstract

Donation after Cardiac Death (DCD) is an important source of kidneys for kidney transplantation, but DCD kidney transplantation is associated with more complications, impacting the function of the transplanted kidney. Establishing a stable DCD kidney transplantation model in rats can help study the mechanisms of injury and complications prevention in DCD kidney transplantation. This review summarizes the current research status and progress in rat DCD kidney transplantation.

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大鼠 DCD 肾移植模型的现状与发展。
心脏死亡后捐献(DCD)是肾移植的重要肾源,但DCD肾移植并发症较多,影响移植肾的功能。建立稳定的 DCD 肾移植大鼠模型有助于研究 DCD 肾移植的损伤和并发症预防机制。本综述总结了大鼠 DCD 肾移植的研究现状和进展。
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