[Risk assessment for complications and stone free status in percutaneous nephrolithotomy].

Jorge Moreno-Palacios, Efraín Maldonado-Alcaraz, Rodolfo Rivas-Ruiz, Romina Vega-Hermosillo, Virgilio Augusto López-Sámano
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Abstract

Background: Percutaneous nephrolithotomy (PNL) is the first line treatment for kidney stones with a diameter > 2 cm. The available scores for measuring success in this procedure only consider the free stone status, without considering the complications.

Objective: To present a new prognostic stratification system to predict treatment failure in PNL.

Material and methods: Historic cohort in which prognostic factors and failure as residual stone with or without complication were identified. A bivariate analysis was performed using the numeric variables and with the use of conjunctive consolidation a prognostic stratification system was developed.

Results: A total of 595 cases were included, out of which 73% concluded with free stone status and 12% developed major complications. 66% fulfilled the proposed success definition. In the first conjunct consolidation, a positive urine culture and a complex stone were identified as risk factors; after making one more conjunction with another stratum, the severe Charlson Comorbidity Index (CCI) was also identified as a risk factor. Finally, an operating time ≥ 120 minutes was added as an intraoperative factor that increases risk.

Conclusions: The variables positive urine culture, severe CCI, complex stone and prolonged operating time are associated with major complications and residual stone. The proposed score is a simple and predictive tool that can be used in daily practice, given that it includes 3 pre-operative variables. The treatment success or failure rate of the score can be applied in the selection of patients ongoing PNL.

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[经皮肾镜取石术并发症和无结石状态的风险评估]。
背景:经皮肾镜取石术(PNL)是治疗直径大于 2 厘米的肾结石的一线疗法。现有的衡量该手术成功与否的评分标准只考虑游离结石的状态,而不考虑并发症:材料与方法:对历史性队列中的预后因素和失败(残余结石伴或不伴并发症)进行识别。使用数字变量进行双变量分析,并使用联合巩固法建立预后分层系统:结果:共纳入了 595 个病例,其中 73% 的病例最终无结石,12% 的病例出现了重大并发症。66%的病例符合建议的成功定义。在第一次结石合并中,尿培养阳性和复杂结石被确定为风险因素;在与另一个分层进行了一次合并后,严重的夏尔森综合症指数(CCI)也被确定为风险因素。最后,手术时间≥120分钟也被认为是增加风险的术中因素:结论:尿培养阳性、严重 CCI、复杂结石和手术时间延长等变量与主要并发症和残余结石有关。鉴于所提出的评分包括 3 个术前变量,因此是一个简单且可用于日常实践的预测工具。该评分的治疗成功率或失败率可用于选择正在进行 PNL 的患者。
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