Hepatic vagus nerve relays signals to the brain that can alter food intake

IF 45.9 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Nature Reviews Gastroenterology &Hepatology Pub Date : 2024-11-29 DOI:10.1038/s41575-024-01028-6
Rebecca Kelsey
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肝迷走神经向大脑传递信号,从而改变食物的摄入量
哺乳动物生物钟的不同步已经知道有害的代谢影响,但如何同步和不同步的信号是不清楚的传输。一项新的研究报道,肝迷走传入神经(HVAN)向大脑传递信号,导致食物摄入的变化,而HVAN的消融可以预防异常的食物摄入。该论文的资深作者Mitch Lazar说:“我们之前报道过,当肝脏中昼夜REV-ERB核受体不起作用时,分子钟的缺陷会导致代谢的变化。”“我们决定看看肝脏时钟是否在限时喂养的影响中起作用。”
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来源期刊
CiteScore
52.30
自引率
0.60%
发文量
147
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.
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