Canine dilated cardiomyopathy. Part 2: manifestations and treatment of clinical DCM

IF 0.3 4区 农林科学 Q4 VETERINARY SCIENCES in Practice Pub Date : 2024-11-28 DOI:10.1002/inpr.494
Andrew Crosland, William Davis, Joanna Dukes-McEwan
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Abstract

Background: Dilated cardiomyopathy (DCM) is the second most common heart disease in dogs, and is more common in large or giant breeds. Physical examination may be unremarkable before the development of clinical signs such as congestive heart failure (CHF), syncopal episodes due to arrhythmias or impaired cardiac output. Different breeds may have different manifestations of DCM, with atrial fibrillation being common in Irish wolfhounds, and ventricular arrhythmias being common in dobermanns. Arrhythmias may coexist or precede development of typical echocardiographic changes of DCM. Idiopathic DCM is believed to have a genetic basis but there can be other causes of the echocardiographic changes that are typical in DCM (called a DCM phenotype), such as nutritional or secondary to primary arrhythmias (tachycardia-induced cardiomyopathy), which need to be excluded. Treatment is palliative and directed at identifying and treating the primary cause of a DCM phenotype, treating CHF or significant arrhythmias. This is the second article in a two-part series on DCM. Part 1, which was published in the November issue of In Practice, focused on the screening, diagnosis and management of preclinical DCM.

Aim of the article: The aim of this article is to update the veterinary surgeon with presentations and manifestations of dogs with DCM, to exclude contributing factors mimicking DCM and to successfully manage affected patients.

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犬扩张型心肌病。第二部分:临床DCM的表现及治疗
背景:扩张型心肌病(DCM)是犬类中第二常见的心脏病,在大型犬或巨型犬中更为常见。在出现诸如充血性心力衰竭(CHF)、由心律失常或心输出量受损引起的晕厥发作等临床症状之前,体格检查可能不显著。不同品种的DCM可能有不同的表现,心房颤动在爱尔兰狼犬中很常见,而室性心律失常在杜宾犬中很常见。心律失常可能共存或先于DCM典型超声心动图改变的发展。特发性DCM被认为有遗传基础,但DCM中典型的超声心动图改变可能有其他原因(称为DCM表型),如营养或继发于原发性心律失常(心动过速诱发的心肌病),这些需要排除。治疗是姑息性的,旨在识别和治疗DCM表型的主要原因,治疗CHF或显著心律失常。这是关于DCM的两篇系列文章中的第二篇。第一部分发表在11月的《in Practice》杂志上,重点介绍了临床前DCM的筛查、诊断和管理。文章的目的:本文的目的是更新兽医与DCM犬的表现和表现,排除诱发DCM的因素,并成功地管理受影响的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
in Practice
in Practice 农林科学-兽医学
CiteScore
0.80
自引率
0.00%
发文量
111
审稿时长
18-36 weeks
期刊介绍: In Practice is published 10 times a year and provides continuing educational material for veterinary practitioners. It includes clinical articles, written by experts in their field and covering all species, providing a regular update on clinical developments, and articles on veterinary practice management. All articles are peer-reviewed. First published in 1979, it now provides an extensive archive of clinical review articles. In Practice is produced in conjunction with Vet Record, the official journal of the British Veterinary Association (BVA). It is published on behalf of the BVA by BMJ Group.
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