Ioannis Anagnostopoulos, Maria Kousta, Dimitrios Vrachatis, Sotiria Giotaki, Dimitra Katsoulotou, Christos Karavasilis, Nikolaos Schizas, Dimitrios Avramides, Georgios Giannopoulos, Spyridon Deftereos
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引用次数: 0
Abstract
Background: Atrial fibrillation (AF) is the commonest supraventricular arrhythmia in adults. Timely AF diagnosis seems to ameliorate patients prognosis.
Purpose: To investigate the association between peak left atrial longitudinal strain (PALS) and new onset AF in the general population.
Objectives: We searched major electronic databases for articles assessing the relationship between PALS and incident AF.
Results: Eight studies (11,145 patients) were analysed. Lower levels of PALS were significantly associated with higher risk of incident AF (HR: 0.95; 95%CI: 0.92-0.97, I2: 83%). According to the diagnostic accuracy meta-analysis, PALS <33.4% presents 64% (95%CI: 46-79%) sensitivity and 69% (95%CI: 63-75%) specificity.
Conclusions: In a relatively healthy population, lower levels of PALS were significantly associated with incident AF. The overall diagnostic accuracy was moderate. Lower levels of PALS seem to justify an opportunistic - rather than a systematic-screening approach. These findings could allow more efficient utilisation of healthcare resources.
期刊介绍:
Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.