Peak left atrial longitudinal strain and incident atrial fibrillation in the general population: a systematic review and meta-analysis.

IF 2.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Acta cardiologica Pub Date : 2024-12-01 Epub Date: 2024-11-29 DOI:10.1080/00015385.2024.2432579

Ioannis Anagnostopoulos, Maria Kousta, Dimitrios Vrachatis, Sotiria Giotaki, Dimitra Katsoulotou, Christos Karavasilis, Nikolaos Schizas, Dimitrios Avramides, Georgios Giannopoulos, Spyridon Deftereos

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Abstract

Background: Atrial fibrillation (AF) is the commonest supraventricular arrhythmia in adults. Timely AF diagnosis seems to ameliorate patients prognosis.

Purpose: To investigate the association between peak left atrial longitudinal strain (PALS) and new onset AF in the general population.

Objectives: We searched major electronic databases for articles assessing the relationship between PALS and incident AF.

Results: Eight studies (11,145 patients) were analysed. Lower levels of PALS were significantly associated with higher risk of incident AF (HR: 0.95; 95%CI: 0.92-0.97, I²: 83%). According to the diagnostic accuracy meta-analysis, PALS <33.4% presents 64% (95%CI: 46-79%) sensitivity and 69% (95%CI: 63-75%) specificity.

Conclusions: In a relatively healthy population, lower levels of PALS were significantly associated with incident AF. The overall diagnostic accuracy was moderate. Lower levels of PALS seem to justify an opportunistic - rather than a systematic-screening approach. These findings could allow more efficient utilisation of healthcare resources.

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普通人群中峰值左心房纵应变和房颤的发生率：一项系统回顾和荟萃分析。

背景：房颤（AF）是成人最常见的室上性心律失常。及时诊断房颤可改善患者预后。目的：探讨普通人群左心房纵应变峰值（PALS）与新发房颤的关系。目的：我们检索了主要电子数据库中评估PALS与af之间关系的文章。结果：我们分析了8项研究（11,145例患者）。较低水平的PALS与较高的AF发生风险显著相关(HR: 0.95；95%ci: 0.92-0.97, i2: 83%)。根据诊断准确性荟萃分析，PALS结论：在相对健康的人群中，较低水平的PALS与AF事件显著相关。总体诊断准确性为中等。较低水平的pal似乎证明了机会主义筛查方法的合理性，而不是系统性筛查方法。这些发现可以更有效地利用医疗资源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta cardiologica 医学-心血管系统

CiteScore

2.50

自引率

12.50%

发文量

115

审稿时长

2 months

期刊介绍： Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.