Sex disparity in the burden of NCDs and its four main subgroups in Iran 1990-2019: a systematic analysis from the global burden of disease study 2019.

IF 1.8 Q4 ENDOCRINOLOGY & METABOLISM Journal of Diabetes and Metabolic Disorders Pub Date : 2024-09-09 eCollection Date: 2024-12-01 DOI:10.1007/s40200-024-01489-1
Mahdie Fatollahzade, Mohammad-Mahdi Bastan, Moez Shaabanian, Ali Golestani, Ozra Tabatabaei-Malazy, MohammadReza Mohajeri-Tehrani, MohammadReza Amini, Sepehr Khosravi, Hamid Pajavand, Bagher Larijani
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Abstract

Objectives: The significant health differences between sexes in Iran in terms of burden of non-communicable diseases (NCDs) point to the urgency of developing policies. We aim to explore sex disparities in NCDs.

Methods: We used Global Burden of Disease 2019 study to compare estimates of incidence, prevalence, disability-adjusted life years (DALYs), years lived with disabilities (YLDs), years of life lost (YLLs), and deaths among sexes for NCDs, and their main subgroups; neoplasms, cardiovascular diseases (CVDs), chronic respiratory diseases (CRDs), diabetes mellitus (DM) during 1990-2019.

Results: In 2019, there were 62,476,274 (59517167.5, 65759931) incident NCDs in men and 78758640.6 (75222093.7, 82272935.8) in women. There were 7734064.3 (6744951.2, 8846192) DALYs in men and 7760484.2 (6496609, 9218299.9) in women. Fatal estimates (deaths and YLLs) of NCDs were higher for men, while non-fatal estimates (prevalence, YLDs) were higher for women. Men were superior in all burden indices of NCDs subgroups, except for all indices of DM and YLDs in CVDs. Compared to 1990-2010, the period 2010-2019 confirmed a marked stagnation in decline rates of burden indices, as well as an increase in incidence and prevalence which was more pronounced among men. Despite shrinking sex gaps in NCDs subgroups since 1990, sex gap in DM is widening in 2019.

Conclusions: There is a notable sex disparity in NCDs prevalence in Iran, which has become increasingly evident in DM burden. It will be imperative to continue monitoring sexual differences in NCDs burden to determine if disease rates between sexes continue to diverge in the future.

Supplementary information: The online version contains supplementary material available at 10.1007/s40200-024-01489-1.

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1990-2019年伊朗非传染性疾病负担及其四个主要亚组的性别差异:来自2019年全球疾病负担研究的系统分析
目标:在非传染性疾病负担方面,伊朗两性之间存在巨大的健康差异,这表明迫切需要制定政策。我们的目标是探索非传染性疾病中的性别差异。方法:我们使用2019年全球疾病负担研究来比较非传染性疾病及其主要亚组的发病率、患病率、残疾调整生命年(DALYs)、残疾生活年(YLDs)、生命损失年(YLLs)和性别间死亡的估计值;肿瘤、心血管疾病(cvd)、慢性呼吸系统疾病(CRDs)、糖尿病(DM)。结果:2019年,男性非传染性疾病发病率为62,476,274例(59517167.5,65759931),女性为78758640.6例(75222093.7,82272935.8)。男性DALYs为7734064.3(6744951.2,8846192),女性为7760484.2(6496609,9218299.9)。非传染性疾病的致命估计值(死亡和生命周期)在男性中较高,而非致命估计值(流行率,生命周期)在女性中较高。除心血管疾病中DM和YLDs的所有指标外,男性在非传染性疾病亚组的所有负担指标中均优于男性。与1990-2010年相比,2010-2019年期间,负担指数的下降速度明显停滞不前,发病率和流行率上升,在男性中更为明显。尽管自1990年以来非传染性疾病亚组的性别差距在缩小,但2019年非传染性疾病亚组的性别差距在扩大。结论:伊朗非传染性疾病患病率存在显著的性别差异,这在糖尿病负担中越来越明显。必须继续监测非传染性疾病负担的性别差异,以确定未来两性之间的发病率是否继续分化。补充资料:在线版本提供补充资料,网址为10.1007/s40200-024-01489-1。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Diabetes and Metabolic Disorders
Journal of Diabetes and Metabolic Disorders Medicine-Internal Medicine
CiteScore
4.80
自引率
3.60%
发文量
210
期刊介绍: Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.
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