Regional cerebral blood flow reflects both neurodegeneration and microvascular integrity across the Alzheimer's continuum

IF 13 1区 医学 Q1 CLINICAL NEUROLOGY Alzheimer's & Dementia Pub Date : 2024-12-03 DOI:10.1002/alz.14382
Mohammad Taghvaei, Sudipto Dolui, Shokufeh Sadaghiani, Banafsheh Shakibajahromi, Christopher Brown, Pulkit Khandelwal, Sharon X. Xie, Sandhitsu Das, Paul A. Yushkevich, David A. Wolk, John A. Detre
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引用次数: 0

Abstract

Alzheimer's disease (AD) typically involves both neurodegenerative and vascular pathologies, each associated with reductions in cerebral blood flow (CBF). However, it remains unclear whether vascular and neural contributions to regional CBF can be differentiated.
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来源期刊
Alzheimer's & Dementia
Alzheimer's & Dementia 医学-临床神经学
CiteScore
14.50
自引率
5.00%
发文量
299
审稿时长
3 months
期刊介绍: Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
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