{"title":"A new synthesis of 7H-pyrrolo[3,2-f]quinoxaline derivatives by a one-pot, three-component reaction","authors":"Xue Wang, Ji Li, Jia-Yan Liu, Dong-Sheng Chen","doi":"10.1007/s12039-024-02332-z","DOIUrl":null,"url":null,"abstract":"<div><p>An acid-catalyzed three-component reaction of arylglyoxals, quinoxalin-6-amine and 4-hydroxycoumarin is described, leading to the synthesis of new functionalized 7<i>H</i>-pyrrolo[3,2-<i>f</i>]quinoxaline derivatives with good yields. It has high synthetic efficiency and operational simplicity, and only water was generated as a byproduct.</p><h3>Graphical abstract</h3><p>A new procedure for the synthesis of pyrrolo[3,2-<i>f</i>]quinoxaline derivatives.\n</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":616,"journal":{"name":"Journal of Chemical Sciences","volume":"136 4","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemical Sciences","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s12039-024-02332-z","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
An acid-catalyzed three-component reaction of arylglyoxals, quinoxalin-6-amine and 4-hydroxycoumarin is described, leading to the synthesis of new functionalized 7H-pyrrolo[3,2-f]quinoxaline derivatives with good yields. It has high synthetic efficiency and operational simplicity, and only water was generated as a byproduct.
Graphical abstract
A new procedure for the synthesis of pyrrolo[3,2-f]quinoxaline derivatives.
期刊介绍：
Journal of Chemical Sciences is a monthly journal published by the Indian Academy of Sciences. It formed part of the original Proceedings of the Indian Academy of Sciences – Part A, started by the Nobel Laureate Prof C V Raman in 1934, that was split in 1978 into three separate journals. It was renamed as Journal of Chemical Sciences in 2004. The journal publishes original research articles and rapid communications, covering all areas of chemical sciences. A significant feature of the journal is its special issues, brought out from time to time, devoted to conference symposia/proceedings in frontier areas of the subject, held not only in India but also in other countries.
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