Studies on monoclonal antibodies reacting with Rh-system antigens

Abstract

Monoclonal antibodies have been shown to be very specific and useful reagents in serology, e.g. mouse monoclonal antibodies against blood group antigens A, B, M, N etc.

But using the mouse monoclonal technology there are only few reports concerning antibodies reacting with Rh-system antigens.

Because of the importance of the anti-Rh-antibodies the human monoclonal antibody technology has been improved and therefore most of the workshop antibodies are human monoclonal antibodies.

These antibodies were tested for their use in routine laboratory work.