Seyed Mohammad Mohammadi, Nadia Saniee, Sajedeh Mousaviasl, Esmat Radmanesh, Amir Hossein Doustimotlagh
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引用次数: 0
Abstract
Background: Osteoporosis is the most common systemic skeletal disease worldwide. We aimed to review the latest studies related to osteocalcin and osteoporosis to clarify this relationship more precisely.
Methods: A systematic literature search was performed to review studies on the effects of osteocalcin on osteoporosis, on studied published between January 2013 and January 2023. We systematically reviewed Web of Science, PubMed, ProQuest, Scopus, and Google Scholar.
Results: The search yielded 4903 records, including 1063 from PubMed, 2307 from Scopus, 1084 from Web of Science, 408 from ProQuest, and 41 from Google Scholar, and twelve articles were included for data extraction and quality assessment. A significant increase in the serum level of osteocalcin was observed in postmenopausal women with osteoporosis (P<0.05), and there was a negative correlation between bone mineral density and the serum level of osteocalcin.
Conclusion: Osteocalcin could be a promising marker for the diagnosis and screening of patients with osteoporosis.
背景：骨质疏松症是世界范围内最常见的系统性骨骼疾病。我们旨在回顾有关骨钙素和骨质疏松症的最新研究，以更准确地阐明这种关系。方法：系统检索2013年1月至2023年1月间发表的关于骨钙素治疗骨质疏松的文献。我们系统地回顾了Web of Science、PubMed、ProQuest、Scopus和谷歌Scholar。结果：共检索到4903条记录，其中PubMed检索1063条，Scopus检索2307条，Web of Science检索1084条，ProQuest检索408条，b谷歌Scholar检索41条，共纳入12篇文章进行数据提取和质量评估。绝经后骨质疏松症患者血清骨钙素水平明显升高(结论：骨钙素可作为骨质疏松症的诊断和筛查指标。
期刊介绍：
Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above mentioned research areas.
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