A Prospective Randomized Comparison of INTELLIVENT-ASV and PSV Modes in Terms of Weaning in Intensive Care Patients, Istanbul, Turkiye.

IF 0.7 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Nigerian Journal of Clinical Practice Pub Date : 2024-11-01 Epub Date: 2024-12-04 DOI:10.4103/njcp.njcp_194_23

D Tatlisuluoglu, G H Alay, G Turan

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Abstract

Background: INTELLIVENT-Adaptive Support Ventilation (I-ASV; C6; Hamilton Medical; Bonaduz, Switzerland) is a closed-loop ventilation mode that continuously controls the patient's ventilation and oxygenation. It sets the minute ventilation, PEEP, and oxygen levels based on the targets set by the clinician and on physiological input from the patient.

Aim: The aim was to compare I-ASV and PSV modes regarding weaning in intensive care patients.

Methods: A total of 140 patients who were over the age of 18 years, did not have a neuromuscular disease, and had been ventilated for at least 48 hours were reviewed. Using the sequential method, patients who met the requirements for weaning were put into two groups: I-ASV and PSV (pressure support ventilation).

Results: The mean age of the I-ASV group (n = 70) and the PSV group (n = 70) was 49.11 ± 17.74 and 49.92 ± 22.00, respectively. In the group using I-ASV, FiO2 was 30.12 ± 10.04%, inspiratory pressure (Pinsp) was 8.71 ± 2.78 cm H2O, and Ppeak value was 11.67 ± 2.78 cm H2O, which were significantly lower than those in the PSV mode (P < 0.001). The PEEP value was significantly lower in the PSV mode (P < 0.001). However, asynchrony-tachycardia was significantly higher in the I-ASV group (28 (20%)) compared to the PSV group (11 (7.9%)) (P < 0.003).

Conclusion: I-ASV mode had no effect on weaning duration compared to PSV mode but decreased PEEP, FiO2, Pinsp, and Ppeak values in weaning patients.

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在土耳其伊斯坦布尔的重症监护患者中，对intellliven - asv和PSV模式进行前瞻性随机比较。

背景：intelligent - adaptive Support Ventilation (I-ASV)；C6;汉密尔顿医疗;Bonaduz, Switzerland)是一种闭环通气模式，持续控制患者的通气和氧合。它根据临床医生设定的目标和患者的生理输入来设定分钟通气量、PEEP和氧气水平。目的：目的是比较重症监护患者的I-ASV和PSV模式。方法：回顾性分析140例18岁以上、无神经肌肉疾病、通气时间≥48小时的患者。采用顺序法，将符合脱机条件的患者分为I-ASV组和PSV组（压力支持通气）。结果：I-ASV组（n = 70）和PSV组（n = 70）的平均年龄分别为49.11±17.74和49.92±22.00。I-ASV组FiO2为30.12±10.04%，吸气压力（Pinsp）为8.71±2.78 cm H2O， Ppeak值为11.67±2.78 cm H2O，均显著低于PSV组（P < 0.001）。PSV模式下PEEP值明显降低（P < 0.001）。然而，I-ASV组的不同步心动过速（28例（20%））明显高于PSV组（11例（7.9%））（P < 0.003）。结论：与PSV模式相比，I-ASV模式对脱机时间无影响，但使脱机患者的PEEP、FiO2、Pinsp、Ppeak值降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nigerian Journal of Clinical Practice MEDICINE, GENERAL & INTERNAL-

CiteScore

1.40

自引率

0.00%

发文量

275

审稿时长

4-8 weeks

期刊介绍： The Nigerian Journal of Clinical Practice is a Monthly peer-reviewed international journal published by the Medical and Dental Consultants’ Association of Nigeria. The journal’s full text is available online at www.njcponline.com. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal makes a token charge for submission, processing and publication of manuscripts including color reproduction of photographs.