Analysis of the Impact of Extraction Processes on the Quality of Traditional Chinese Medicine Granules.

IF 3 3区生物学 Q2 BIOCHEMICAL RESEARCH METHODS Phytochemical Analysis Pub Date : 2024-12-02 DOI:10.1002/pca.3484

Cong Zhang, Chungang Zhang, Meng Liu, Ti Wang

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Abstract

Objective: This review aims to summarize and elucidate the extraction processes of traditional Chinese medicine granules, examining their connection to quality control, with the aim of establishing a foundation for superior extraction methodologies.

Methodology: This article systematically collects and analyzes relevant literature from the past two decades through databases such as Science Direct, PubMed, Web of Science, Google Scholar, and CNKI, focusing on the extraction processes of traditional Chinese medicine granules and the factors affecting extraction efficiency.

Results: This article provides a comprehensive account of the extraction and granulation processes of traditional Chinese medicine granules. Beginning with the physicochemical properties and chemical components of herbal slices, it explores ways to improve extraction efficiency while also examining the relationship between component structure and biological activity. Rooted in the fundamental theories of traditional Chinese medicine and harmonized with contemporary extraction technologies, it follows the principle that "quality originates from design," ensuring stringent control over the extraction process.

Conclusion: This article analyzes extraction technologies, factors influencing extraction efficiency, and quality control measures, establishing a theoretical basis for achieving high-quality and high-yield extraction processes.

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提取工艺对中药颗粒质量的影响分析。

目的：综述中药颗粒的提取工艺，探讨其与质量控制的关系，为优选提取方法奠定基础。方法：通过Science Direct、PubMed、Web of Science、谷歌Scholar、CNKI等数据库，系统收集和分析近二十年来的相关文献，重点研究中药颗粒的提取工艺及提取效率的影响因素。结果：对中药颗粒的提取和造粒工艺进行了较为全面的研究。从中药饮片的理化性质和化学成分入手，探讨提高提取效率的方法，同时考察成分结构与生物活性之间的关系。它植根于传统中医的基本理论，并与现代提取技术相协调，遵循“品质源于设计”的原则，确保对提取过程的严格控制。结论：本文分析了提取工艺、影响提取效率的因素及质量控制措施，为实现高质量、高产率的提取工艺奠定了理论基础。

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来源期刊

Phytochemical Analysis 生物-分析化学

CiteScore

6.00

自引率

6.10%

发文量

审稿时长

1.7 months

期刊介绍： Phytochemical Analysis is devoted to the publication of original articles concerning the development, improvement, validation and/or extension of application of analytical methodology in the plant sciences. The spectrum of coverage is broad, encompassing methods and techniques relevant to the detection (including bio-screening), extraction, separation, purification, identification and quantification of compounds in plant biochemistry, plant cellular and molecular biology, plant biotechnology, the food sciences, agriculture and horticulture. The Journal publishes papers describing significant novelty in the analysis of whole plants (including algae), plant cells, tissues and organs, plant-derived extracts and plant products (including those which have been partially or completely refined for use in the food, agrochemical, pharmaceutical and related industries). All forms of physical, chemical, biochemical, spectroscopic, radiometric, electrometric, chromatographic, metabolomic and chemometric investigations of plant products (monomeric species as well as polymeric molecules such as nucleic acids, proteins, lipids and carbohydrates) are included within the remit of the Journal. Papers dealing with novel methods relating to areas such as data handling/ data mining in plant sciences will also be welcomed.