Prenatal-Postnatal Outcomes and Prognostic Risk Factors of Fetal Volvulus: Analysis of 26 Cases.

IF 2.7 2区 医学 Q2 GENETICS & HEREDITY Prenatal Diagnosis Pub Date : 2025-01-01 Epub Date: 2024-12-03 DOI:10.1002/pd.6718
Ümit Taşdemir, Ömer Gökhan Eyisoy, Murad Gezer, Ayşenur Celayir, Mucize Eriç Özdemir, Oya Demirci
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Abstract

Objective: The aim of the current study was to reveal ultrasonographic and clinical features, prenatal-postnatal outcomes and prognostic risk factors of fetal volvulus.

Method: This retrospective study evaluated all cases of fetal volvulus diagnosed between 2018 and 2024 at the Perinatology center of Zeynep Kamil Women and Children Diseases Training and Research Hospital. In the vast majority of cases, the pediatric surgery team confirmed the conclusive diagnosis of volvulus during the postnatal period. The cohort was divided into two groups, the "survivor" and "deceased", in order to compare the outcome and to evaluate factors determining the outcome.

Result: A total of 26 cases of fetal volvulus were followed up in our perinatology center which were confirmed by postnatal pediatric surgery or autopsy. Termination of pregnancy in two cases and intrauterine fetal death in one case were observed. Twenty-three cases reached live birth. Preterm labor, fetal growth restriction, ascites and decreased intestinal peristalsis were significantly more common in the deceased group. Neonatal death in five cases (19.2%), infant death in four cases (15.3%) and short gut syndrome in three cases (11.5%) were long term outcomes.

Conclusion: Overall mortality rate may increase when fetal growth restriction, ascites, and decreased intestinal peristalsis are present with volvulus.

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胎儿扭转26例产前、产后结局及预后危险因素分析。
目的:探讨胎儿扭转的超声、临床特征、产前、产后结局及预后危险因素。方法:对泽伊内普卡米尔妇幼疾病培训研究医院围产期中心2018 - 2024年诊断的所有胎儿扭转病例进行回顾性研究。在绝大多数情况下,儿科外科团队确认了产后扭转的结论性诊断。该队列被分为两组,“幸存者”和“死者”,以比较结果和评估决定结果的因素。结果:本院围产中心共随访26例胎儿扭转,经产后小儿手术或尸检证实。观察到2例终止妊娠,1例宫内胎儿死亡。23例活产。早产、胎儿生长受限、腹水和肠道蠕动减少在死者组中更为常见。新生儿死亡5例(19.2%),婴儿死亡4例(15.3%),短肠综合征3例(11.5%)为长期结局。结论:当胎儿生长受限、腹水、肠蠕动减少并伴有肠扭转时,总死亡率可能增加。
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来源期刊
Prenatal Diagnosis
Prenatal Diagnosis 医学-妇产科学
CiteScore
5.80
自引率
13.30%
发文量
204
审稿时长
2 months
期刊介绍: Prenatal Diagnosis welcomes submissions in all aspects of prenatal diagnosis with a particular focus on areas in which molecular biology and genetics interface with prenatal care and therapy, encompassing: all aspects of fetal imaging, including sonography and magnetic resonance imaging; prenatal cytogenetics, including molecular studies and array CGH; prenatal screening studies; fetal cells and cell-free nucleic acids in maternal blood and other fluids; preimplantation genetic diagnosis (PGD); prenatal diagnosis of single gene disorders, including metabolic disorders; fetal therapy; fetal and placental development and pathology; development and evaluation of laboratory services for prenatal diagnosis; psychosocial, legal, ethical and economic aspects of prenatal diagnosis; prenatal genetic counseling
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